Evidence map›Paper›PMID 38866556›Full record

ArticleGenes & development2024

Genome organization regulates nuclear pore complex formation and promotes differentiation during

Noor M Kotb, Gulay Ulukaya, Ankita Chavan, Son C Nguyen, Lydia Proskauer, Eric F Joyce, Dan Hasson, Madhav Jagannathan, Prashanth Rangan

Abstract read
In one paragraph

Article in Genes & development, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Stress transmission towards the nucleus of the cell.Frontiers in cell and developmental biology · 2026
    Review
  5. bioRxiv : the preprint server for biology · 2025
    Article
  6. Cells · 2025
    Review
  7. Article
  8. A nuclear architecture screen inGenes & development · 2024
    Article
  9. A nuclear architecture screen inbioRxiv : the preprint server for biology · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Noor M KotbDepartment of Biomedical Sciences/Wadsworth Center, University at Albany State University of New York (SUNY), Albany, New York 12202, USA.
Gulay UlukayaDepartment of Cell, Developmental, and Regenerative Biology, Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NewYork 10029, USA.
Ankita ChavanInstitute of Biochemistry, Department of Biology, Eidgenössische Technische Hochschule (ETH) Zürich, 8092 Zürich, Switzerland.
Son C NguyenDepartment of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Lydia ProskauerDepartment of Biological Sciences/RNA Institute, University at Albany SUNY, Albany, New York 12202, USA.
Eric F JoyceDepartment of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Dan HassonDepartment of Cell, Developmental, and Regenerative Biology, Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NewYork 10029, USA.
Madhav JagannathanInstitute of Biochemistry, Department of Biology, Eidgenössische Technische Hochschule (ETH) Zürich, 8092 Zürich, Switzerland.ORCID 0000-0003-3428-6812
Prashanth RanganDepartment of Cell, Developmental, and Regenerative Biology, Black Family Stem Cell Institute, Icahn School of Medicine at Mount Sinai, New York, NewYork 10029, USA; prashanth.rangan@mssm.edu.

Funding

Conduits: Mount Sinai Health System Translational Science HubUL1TR004419 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Rosalind J Wright · 2022 to 2026
$46.4M
THE TISCH CANCER INSTITUTE - CANCER CENTER SUPPORT GRANTP30CA196521 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Ramon E Parsons · 2015 to 2026
$35.4M
Regulation of stem cell differentiation during Drosophila oogenesisR01GM111779 · NIGMS · STATE UNIVERSITY OF NEW YORK AT ALBANY · PI RANGAN, PRASHANTH · 2014 to 2022
$2.7M
COVID and Translational Science supercomputer (CATS)S10OD030463 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KOVATCH, PATRICIA · 2021 to 2021
$2.0M
Big Omics Data Engine 2 SupercomputerS10OD026880 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KOVATCH, PATRICIA · 2019 to 2019
$2.0M
Role of RNA degradation in germline stem cell to oocyte transitionR01GM135628 · NIGMS · STATE UNIVERSITY OF NEW YORK AT ALBANY · PI RANGAN, PRASHANTH · 2020 to 2023
$1.3M
Cellular rejuvenation during oogenesisR56AG082906 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CAPELSON, MAYA, RANGAN, PRASHANTH · 2023 to 2023
$387k
NCATS NIH HHS UL1 TR004419NCI NIH HHS P30 CA196521NIA NIH HHS R56 AG082906NIGMS NIH HHS R01 GM111779NIGMS NIH HHS R01 GM135628NIH HHS S10 OD026880NIH HHS S10 OD030463
6 · The paper itself

Abstract

Genome organization can regulate gene expression and promote cell fate transitions. The differentiation of germline stem cells (GSCs) to oocytes in

Indexed as

Cell DifferentiationDrosophila ProteinsGenome, InsectNuclear PoreOogenesisAnimalsDrosophilaDrosophila melanogasterFemaleGene Expression Regulation, DevelopmentalNuclear Pore Complex ProteinsOocytesTranscription FactorsDrosophila ProteinsNuclear Pore Complex ProteinsTranscription Factorsdifferentiationgenome organizationheterochromatinLADlaminNPCnucleoporinsTAD

Identifiers

PMID38866556
PMCPMC11216175

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.