Evidence map›Paper›PMID 38866404›Full record

ArticleBJGP open2024

Evaluating the benefits of machine learning for diagnosing deep vein thrombosis compared with gold standard ultrasound: a feasibility study.

Kerstin Nothnagel, Mohammed Farid Aslam

Registry-linked trialAbstract read
In one paragraph

Article in BJGP open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06652568 (Determining the Validity of ThinkSono Guidance for Ultrasound Image Acquisition and Remote Detection), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06652568 nacompletednot on this map

Determining the Validity of ThinkSono Guidance for Ultrasound Image Acquisition and Remote Detection

TypeinterventionalSponsorThinkSono, Ltd.Ran2023 to 2025Enrolled634ConditionsDeep Vein Thrombosis, Deep Vein Thrombosis, Pulmonary EmbolusArmsThinkSono System
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kerstin NothnagelPopulation Health Sciences, Canynge Hall, Bristol Medical School, University of Bristol, Bristol, UK Kerstin.Nothnagel@bristol.ac.uk.ORCID https://orcid.org/0009-0004-5767-8346
Mohammed Farid AslamImperial College London, London, England, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study evaluates the feasibility of remote deep venous thrombosis (DVT) diagnosis via ultrasound sequences facilitated by ThinkSono Guidance, an artificial intelligence (AI) app for point-of-care ultrasound (POCUS).

aimTo assess the effectiveness of AI-guided POCUS conducted by non-specialists in capturing valid ultrasound images for remote diagnosis of DVT. DESIGN &

settingOver a 3.5-month period, patients with suspected DVT underwent AI-guided POCUS conducted by non-specialists using a handheld ultrasound probe connected to the app. These ultrasound sequences were uploaded to a cloud dashboard for remote specialist review. Additionally, participants received formal DVT scans.

methodPatients underwent AI-guided POCUS using handheld probes connected to the AI app, followed by formal DVT scans. Ultrasound sequences acquired during the AI-guided scan were uploaded to a cloud dashboard for remote specialist review, where image quality was assessed, and diagnoses were provided.

resultsAmong 91 predominantly older female participants, 18% of scans were incomplete. Of the rest, 91% had sufficient quality, with 64% categorised by remote clinicians as 'compressible' or 'incompressible'. Sensitivity and specificity for adequately imaged scans were 100% and 91%, respectively. Notably, 53% were low risk, potentially obviating formal scans.

conclusionThinkSono Guidance effectively directed non-specialists, streamlining DVT diagnosis and treatment. It may reduce the need for formal scans, particularly with negative findings, and extend diagnostic capabilities to primary care. The study highlights AI-assisted POCUS potential in improving DVT assessment.

Indexed as

artificial intelligenceclinical (general)diagnosisscreeningvenous thrombosis

Identifiers

PMID38866404
PMCPMC11687269

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.