Evidence map›Paper›PMID 38866051›Full record

ArticleNature2024

Interactions between immune cell types facilitate the evolution of immune traits.

Tania Dubovik, Martin Lukačišin, Elina Starosvetsky, Benjamin LeRoy, Rachelly Normand, Yasmin Admon, Ayelet Alpert, Yishai Ofran, Max G'Sell, Shai S Shen-Orr

Abstract read
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Genomic-microbial coevolution in human development: chromosome 2 fusion, and human accelerated regions.Mammalian genome : official journal of the International Mammalian Genome Society · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Immuno-oncology recapitulates ontogeny: Modern cell and gene therapy for cancer.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tania Dubovik *Department of Immunology, Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel.
Martin Lukačišin *Department of Immunology, Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel.ORCID 0000-0001-6549-4177
Elina StarosvetskyDepartment of Immunology, Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel.
Benjamin LeRoyDepartment of Statistics, Carnegie Mellon University, Pittsburgh, PA, USA.
Rachelly NormandDepartment of Immunology, Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel.
Yasmin AdmonDepartment of Immunology, Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel.
Ayelet AlpertDepartment of Immunology, Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel.
Yishai OfranDepartment of Immunology, Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel.
Max G'SellDepartment of Statistics, Carnegie Mellon University, Pittsburgh, PA, USA.
Shai S Shen-OrrDepartment of Immunology, Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel. shenorr@technion.ac.il.ORCID 0000-0002-6991-7736

Funding

The effects of immune-age on immune-response and the molecular mechanisms which drive itP01AI153559 · NIAID · STANFORD UNIVERSITY · PI SHEN-ORR, SHAI SHLOMO · 2021 to 2025
$17.8M
NIAID NIH HHS P01 AI153559
6 · The paper itself

Abstract

An essential prerequisite for evolution by natural selection is variation among individuals in traits that affect fitness

Indexed as

Biological EvolutionCell CommunicationImmune SystemSelection, GeneticAnimalsCell DeathCell MovementCell ProliferationHomeostasisHumansMaleMiceMultifactorial InheritancePhenotype

Identifiers

PMID38866051
PMCPMC11306095

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.