Evidence map›Paper›PMID 38865462›Full record

ArticleScience advances2024

Sex-dependent regulation of vertebrate somatic growth and aging by germ cells.

Kota Abe, Hikaru Ino, Tomomi Niwa, Daniel Semmy, Ayami Takaochi, Takashi Nishimura, Chihiro Mogi, Maki Uenaka, Masaru Ishii, Kaori Tanaka and 2 more

Abstract read
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kota AbeDepartment of Homeostatic Regulation, Division of Cellular and Molecular Biology, Research Institute for Microbial Diseases, Osaka University, Suita, Japan.ORCID 0009-0003-5835-5867
Hikaru InoDepartment of Homeostatic Regulation, Division of Cellular and Molecular Biology, Research Institute for Microbial Diseases, Osaka University, Suita, Japan.
Tomomi NiwaDepartment of Homeostatic Regulation, Division of Cellular and Molecular Biology, Research Institute for Microbial Diseases, Osaka University, Suita, Japan.
Daniel SemmyDepartment of Homeostatic Regulation, Division of Cellular and Molecular Biology, Research Institute for Microbial Diseases, Osaka University, Suita, Japan.
Ayami TakaochiDepartment of Homeostatic Regulation, Division of Cellular and Molecular Biology, Research Institute for Microbial Diseases, Osaka University, Suita, Japan.
Takashi NishimuraMetabolic Regulation and Genetics, Department of Molecular and Cellular Biology, Institute for Molecular and Cellular Regulation, Gunma University, Maebashi, Japan.ORCID 0000-0002-6773-0302
Chihiro MogiInstitute for Molecular and Cellular Regulation, Gunma University, Maebashi, Japan.ORCID 0000-0003-4356-2567
Maki UenakaDepartment of Immunology and Cell Biology, Graduate School of Medicine / Graduate School of Frontier Biosciences, Osaka University, Suita, Japan.ORCID 0000-0002-2204-0551
Masaru IshiiDepartment of Immunology and Cell Biology, Graduate School of Medicine / Graduate School of Frontier Biosciences, Osaka University, Suita, Japan.ORCID 0000-0002-4215-007X
Kaori TanakaDivision of Transcriptomics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
Yasuyuki OhkawaDivision of Transcriptomics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.ORCID 0000-0001-6440-9954
Tohru IshitaniDepartment of Homeostatic Regulation, Division of Cellular and Molecular Biology, Research Institute for Microbial Diseases, Osaka University, Suita, Japan.ORCID 0000-0002-6200-7043

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The function of germ cells in somatic growth and aging has been demonstrated in invertebrate models but remains unclear in vertebrates. We demonstrated sex-dependent somatic regulation by germ cells in the short-lived vertebrate model

Indexed as

AgingGerm CellsInsulin-Like Growth Factor IAnimalsBody SizeEstrogensFemaleMaleSex CharacteristicsSignal TransductionVertebratesVitamin DEstrogensInsulin-Like Growth Factor IVitamin D

Identifiers

PMID38865462
PMCPMC11168456

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.