Evidence map›Paper›PMID 38865452›Full record

ArticleScience advances2024

Genetic variants that modify neuroendocrine gene expression and foraging behavior of

Harksun Lee, Sonia A Boor, Zoë A Hilbert, Joshua D Meisel, Jaeseok Park, Ye Wang, Ryan McKeown, Sylvia E J Fischer, Erik C Andersen, Dennis H Kim

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Harksun LeeDivision of Infectious Diseases, Department of Pediatrics, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.ORCID 0009-0009-9538-1945
Sonia A BoorDivision of Infectious Diseases, Department of Pediatrics, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0001-5480-3659
Zoë A HilbertDepartment of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.ORCID 0000-0002-3833-6912
Joshua D MeiselDepartment of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.ORCID 0000-0002-6944-5177
Jaeseok ParkDivision of Infectious Diseases, Department of Pediatrics, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.
Ye WangDepartment of Molecular Biosciences, Northwestern University, Evanston, IL 60208, USA.
Ryan McKeownDepartment of Molecular Biosciences, Northwestern University, Evanston, IL 60208, USA.ORCID 0000-0003-3570-2494
Sylvia E J FischerDivision of Infectious Diseases, Department of Pediatrics, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0003-4290-0093
Erik C AndersenDepartment of Biology, Johns Hopkins University, Baltimore, MD 21212, USA.ORCID 0000-0003-0229-9651
Dennis H KimDivision of Infectious Diseases, Department of Pediatrics, Boston Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0002-4109-5152

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
Microbial Modulation of Physiology and Behavior of C. elegansR35GM141794 · NIGMS · BOSTON CHILDREN'S HOSPITAL · PI Dennis H Kim · 2021 to 2026
$2.6M
NIGMS NIH HHS R35 GM141794NIH HHS P40 OD010440
6 · The paper itself

Abstract

The molecular mechanisms underlying diversity in animal behavior are not well understood. A major experimental challenge is determining the contribution of genetic variants that affect neuronal gene expression to differences in behavioral traits. In

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsGenetic VariationAnimalsBehavior, AnimalFeeding BehaviorGene Expression RegulationNeuronsNeurosecretory SystemsSignal TransductionTransforming Growth Factor betaCaenorhabditis elegans ProteinsDAF-7 protein, C elegansTransforming Growth Factor beta

Identifiers

PMID38865452
PMCPMC11168454

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.