Evidence map›Paper›PMID 38865301›Full record

ArticleACS chemical biology2024

High-Resolution Substrate Specificity Profiling of SARS-CoV-2 M

Rasha M Yaghi, Collin L Andrews, Dennis C Wylie, Brent L Iverson

Abstract readComparative Study
In one paragraph

Article in ACS chemical biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. The C117D oxidation mimic reveals the monomeric structure of SARS-CoV-2 main protease.Protein science : a publication of the Protein Society · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Dissecting the effects of single amino acid substitutions in SARS-CoV-2 Mpro.Protein science : a publication of the Protein Society · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rasha M YaghiDepartment of Chemistry, University of Texas at Austin, Austin, Texas 78712, United States of America.ORCID 0009-0006-8639-497X
Collin L AndrewsDepartment of Chemistry, University of Texas at Austin, Austin, Texas 78712, United States of America.
Dennis C WylieCenter of Biomedical Research Support, University of Texas at Austin, Austin, Texas 78712, United States of America.
Brent L IversonDepartment of Chemistry, University of Texas at Austin, Austin, Texas 78712, United States of America.ORCID 0000-0001-7974-3605

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The SARS-CoV-2 M

Indexed as

Coronavirus 3C ProteasesSARS-CoV-2COVID-19HumansSubstrate SpecificityViral Nonstructural ProteinsCoronavirus 3C ProteasesORF1ab polyprotein, SARS-CoV-2Viral Nonstructural Proteins

Identifiers

PMID38865301
PMCPMC11267570

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.