Evidence map›Paper›PMID 38865274›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Membralin is required for maize development and defines a branch of the endoplasmic reticulum-associated degradation pathway in plants.

Baiyu Liu, Changzheng Xu, Qiuxia He, Ke Zhang, Shoumei Qi, Zhe Jin, Wen Cheng, Zhaohua Ding, Donghua Chen, Xiangyu Zhao and 3 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Baiyu Liu *The Key Laboratory of Plant Development and Environment Adaptation Biology, Ministry of Education, School of Life Science, Shandong University, Qingdao 266237, China.ORCID 0009-0006-9802-0916
Changzheng Xu *School of Life Sciences, Southwest University, Chongqing 400715, China.ORCID 0000-0002-4048-3620
Qiuxia He *Science and Technology Service Platform, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250103, China.ORCID 0000-0001-9096-8637
Ke Zhang *The Key Laboratory of Plant Development and Environment Adaptation Biology, Ministry of Education, School of Life Science, Shandong University, Qingdao 266237, China.ORCID 0009-0005-0484-7676
Shoumei QiThe Key Laboratory of Plant Development and Environment Adaptation Biology, Ministry of Education, School of Life Science, Shandong University, Qingdao 266237, China.ORCID 0009-0003-2027-2812
Zhe JinThe Key Laboratory of Plant Development and Environment Adaptation Biology, Ministry of Education, School of Life Science, Shandong University, Qingdao 266237, China.ORCID 0009-0006-2141-2057
Wen ChengMaize Institute of Shandong Academy of Agricultural Sciences, Jinan, Shandong 250100, China.ORCID 0000-0003-3975-0389
Zhaohua DingMaize Institute of Shandong Academy of Agricultural Sciences, Jinan, Shandong 250100, China.ORCID 0009-0006-2869-582X
Donghua ChenThe Key Laboratory of Plant Development and Environment Adaptation Biology, Ministry of Education, School of Life Science, Shandong University, Qingdao 266237, China.ORCID 0000-0002-4902-8800
Xiangyu ZhaoState Key Laboratory of Crop Biology, College of Life Sciences, Shandong Agricultural University, Taian, Shandong 271018, China.ORCID 0000-0002-6809-6542
Wei ZhangThe Key Laboratory of Plant Development and Environment Adaptation Biology, Ministry of Education, School of Life Science, Shandong University, Qingdao 266237, China.ORCID 0000-0002-6077-9138
Kewei ZhangThe Key Laboratory of Plant Development and Environment Adaptation Biology, Ministry of Education, School of Life Science, Shandong University, Qingdao 266237, China.ORCID 0000-0002-4343-5835
Kunpeng LiThe Key Laboratory of Plant Development and Environment Adaptation Biology, Ministry of Education, School of Life Science, Shandong University, Qingdao 266237, China.ORCID 0000-0003-1807-4545

Funding

Key R&D Program of Shandong Province, China 2021LZGC022 and 2023LZGC003MOST | National Natural Science Foundation of China (NSFC) 32072070 and 32372113Shandong Zhongnong Tiantai Seeds Co., Ltd 1200020002
6 · The paper itself

Abstract

Endoplasmic reticulum (ER)-associated degradation (ERAD) plays key roles in controlling protein levels and quality in eukaryotes. The Ring Finger Protein 185 (RNF185)/membralin ubiquitin ligase complex was recently identified as a branch in mammals and is essential for neuronal function, but its function in plant development is unknown. Here, we report the map-based cloning and characterization of

Indexed as

Endoplasmic Reticulum-Associated DegradationPlant ProteinsUbiquitin-Protein LigasesZea maysAnimalsArabidopsisArabidopsis ProteinsEndoplasmic ReticulumEndoplasmic Reticulum StressGene Expression Regulation, PlantMembrane ProteinsMicePlant LeavesUnfolded Protein ResponseArabidopsis ProteinsMembrane ProteinsPlant ProteinsUbiquitin-Protein Ligasesendoplasmic reticulum–associated degradationmaizemembralinplant developmentunfold protein response

Identifiers

PMID38865274
PMCPMC11194580

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.