Evidence map›Paper›PMID 38865264›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Hundreds of antimicrobial peptides create a selective barrier for insect gut symbionts.

Joy Lachat, Gaëlle Lextrait, Romain Jouan, Amira Boukherissa, Aya Yokota, Seonghan Jang, Kota Ishigami, Ryo Futahashi, Raynald Cossard, Delphine Naquin and 9 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. InferiorMicrobial genomics · 2024
    Pooled it
  2. Artificial intelligence catalyzes antimicrobial peptide design.Synthetic and systems biotechnology · 2027
    Review
  3. Article
  4. SymbioticmBio · 2026
    Article
  5. Article
  6. Article
  7. Fidelity in co-diversified symbiosis.Nature communications · 2026
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Ingested soil bacteria breach gut epithelia and prime systemic immunity in an insect.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Joy Lachat *Université Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell, Gif-sur-Yvette 91198, France.
Gaëlle Lextrait *Université Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell, Gif-sur-Yvette 91198, France.
Romain Jouan *Université Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell, Gif-sur-Yvette 91198, France.
Amira BoukherissaUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell, Gif-sur-Yvette 91198, France.
Aya YokotaUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell, Gif-sur-Yvette 91198, France.ORCID 0009-0000-0454-3633
Seonghan JangBioproduction Research Institute, National Institute of Advanced Industrial Science and Technology, Hokkaido Center, Sapporo 062-8517, Japan.ORCID 0000-0002-0486-3351
Kota IshigamiBioproduction Research Institute, National Institute of Advanced Industrial Science and Technology, Hokkaido Center, Sapporo 062-8517, Japan.
Ryo FutahashiBioproduction Research Institute, National Institute of Advanced Industrial Science and Technology, Tsukuba 305-8566, Japan.ORCID 0000-0003-4791-7054
Raynald CossardUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell, Gif-sur-Yvette 91198, France.
Delphine NaquinUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell, Gif-sur-Yvette 91198, France.ORCID 0000-0001-9174-4686
Vlad CostacheMIMA2 Imaging Core Facility, Microscopie et Imagerie des Microorganismes, Animaux et Aliments (MIMA2), INRAe, Jouy-en-Josas 78352, France.ORCID 0000-0003-0468-3104
Luis AugustoUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell, Gif-sur-Yvette 91198, France.
Pierre TissièresUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell, Gif-sur-Yvette 91198, France.ORCID 0000-0001-5423-5532
Emanuele G BiondiUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell, Gif-sur-Yvette 91198, France.
Benoît AlunniUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell, Gif-sur-Yvette 91198, France.
Tatiana TimchenkoUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell, Gif-sur-Yvette 91198, France.ORCID 0009-0003-4958-6073
Tsubasa OhbayashiUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell, Gif-sur-Yvette 91198, France.ORCID 0000-0002-6912-7021
Yoshitomo KikuchiBioproduction Research Institute, National Institute of Advanced Industrial Science and Technology, Hokkaido Center, Sapporo 062-8517, Japan.ORCID 0000-0002-1651-2532
Peter MergaertUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell, Gif-sur-Yvette 91198, France.ORCID 0000-0002-5919-7317

Funding

Agence Nationale de la Recherche (ANR) ANR-19-CE20-0007MEXT | Japan Society for the Promotion of Science (JSPS) 14J03996MEXT | Japan Society for the Promotion of Science (JSPS) 19J01106MEXT | Japan Society for the Promotion of Science (JSPS) 20170267MEXT | Japan Society for the Promotion of Science (JSPS) 21F21090MEXT | Japan Society for the Promotion of Science (JSPS) 22KJ0057MEXT KAKENHI 21K18241MEXT KAKENHI 22H05068
6 · The paper itself

Abstract

The spatial organization of gut microbiota is crucial for the functioning of the gut ecosystem, although the mechanisms that organize gut bacterial communities in microhabitats are only partially understood. The gut of the insect

Indexed as

Antimicrobial PeptidesGastrointestinal MicrobiomeSymbiosisAnimalsBacteriaGastrointestinal TractAntimicrobial Peptidesantimicrobial peptidesgut microbiotainsectssymbiosis

Identifiers

PMID38865264
PMCPMC11194567

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.