Evidence map›Paper›PMID 38865263›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Argonaute-independent, Dicer-dependent antiviral defense against RNA viruses.

Yukiyo Sato, Hideki Kondo, Nobuhiro Suzuki

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yukiyo SatoInstitute of Plant Science and Resources, Okayama University, Kurashiki, Okayama 710-0046, Japan.
Hideki KondoInstitute of Plant Science and Resources, Okayama University, Kurashiki, Okayama 710-0046, Japan.ORCID 0000-0001-9220-5350
Nobuhiro SuzukiInstitute of Plant Science and Resources, Okayama University, Kurashiki, Okayama 710-0046, Japan.ORCID 0000-0003-0097-9856

Funding

MEXT | Japan Society for the Promotion of Science (JSPS) 19J00261MEXT | Japan Society for the Promotion of Science (JSPS) 22F22095 21H05035 21K18222 16H06436 16H06429
6 · The paper itself

Abstract

Antiviral RNA interference (RNAi) is conserved from yeasts to mammals. Dicer recognizes and cleaves virus-derived double-stranded RNA (dsRNA) and/or structured single-stranded RNA (ssRNA) into small-interfering RNAs, which guide effector Argonaute to homologous viral RNAs for digestion and inhibit virus replication. Thus, Argonaute is believed to be essential for antiviral RNAi. Here, we show Argonaute-independent, Dicer-dependent antiviral defense against dsRNA viruses using

Indexed as

Ribonuclease IIIRNA VirusesArgonaute ProteinsAscomycotaFungal ProteinsRNA, Double-StrandedRNA InterferenceRNA, ViralVirus ReplicationArgonaute ProteinsFungal ProteinsRibonuclease IIIRNA, Double-StrandedRNA, ViralArgonautechestnut blightDicerfungal virusRNAi

Identifiers

PMID38865263
PMCPMC11194562

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.