Evidence map›Paper›PMID 38864291›Full record

ArticleTransfusion2024

Modeling US blood donor deferrals under a policy of individual risk assessment for HIV risk sexual behavior.

Barbee I Whitaker, Yin Huang, Diane Gubernot, Anne F Eder, Debby Herbenick, Tsung-Chieh Fu, Richard A Forshee, Steven A Anderson

Abstract read
In one paragraph

Article in Transfusion, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Barbee I WhitakerFDA Center for Biologics Evaluation and Research, Office of Biostatistics and Pharmacovigilance, Silver Spring, Maryland, USA.ORCID 0000-0002-6311-6268
Yin HuangFDA Center for Biologics Evaluation and Research, Office of Biostatistics and Pharmacovigilance, Silver Spring, Maryland, USA.ORCID 0000-0001-7333-2784
Diane GubernotFDA Center for Biologics Evaluation and Research, Office of Biostatistics and Pharmacovigilance, Silver Spring, Maryland, USA.
Anne F EderFDA Center for Biologics Evaluation and Research, Office of Blood Research and Review, Silver Spring, Maryland, USA.ORCID 0000-0003-2328-626X
Debby HerbenickCenter for Sexual Health Promotion, Indiana University, Bloomington, Indiana, USA.
Tsung-Chieh FuCenter for Sexual Health Promotion, Indiana University, Bloomington, Indiana, USA.
Richard A ForsheeFDA Center for Biologics Evaluation and Research, Office of Biostatistics and Pharmacovigilance, Silver Spring, Maryland, USA.
Steven A AndersonFDA Center for Biologics Evaluation and Research, Office of Biostatistics and Pharmacovigilance, Silver Spring, Maryland, USA.

Funding

Sexual Health and Behavior in a U.S. Probability Sample of Adolescents and AdultsR01HD102535 · NICHD · TRUSTEES OF INDIANA UNIVERSITY · PI FU, TSUNG-CHIEH (JANE), HERBENICK, DEBRA LYNNE · 2021 to 2024
$2.5M
NICHD NIH HHS R01 HD102535NIH HHS R01HD102535
6 · The paper itself

Abstract

backgroundIn May 2023, the Food and Drug Administration (FDA) released final guidance for blood donor eligibility that recommended the elimination of 3-month deferral for men who have sex with men (MSM) and the related deferral for women who have sex with MSM. In its place, FDA introduced an individual risk assessment policy of asking all presenting blood donors, regardless of sex or gender, if they have had a new partner or more than one sexual partner in the last 3 months and deferring those who also report anal sex (penile-anal intercourse) during this period. We modeled the possible impact of this policy on the US blood donor base. STUDY DESIGN AND

methodsWe developed a computational model to estimate the percentage of blood donors who would be deferred under a policy of individual HIV risk assessment. The model incorporated demographic information about donors and national survey data on HIV risk behaviors and included age and sex distributions and dependencies.

resultsOur model estimates that approximately 1.2% of US blood donors would be deferred under the individual HIV risk assessment paradigm. DISCUSSION: The model predicts a relatively minor effect of replacing the time-based deferral for MSM with individual risk-based deferral for sexual behavior. As US blood centers implement this new policy, the effect may be mitigated by donor gains, which warrant further study. The new policy is unlikely to adversely affect the availability of blood and blood components.

Indexed as

Blood DonorsHIV InfectionsSexual BehaviorAdolescentAdultDonor SelectionFemaleHomosexuality, MaleHumansMaleMiddle AgedRisk AssessmentRisk-TakingUnited StatesYoung Adultanal sexblood donor deferralblood donor lossHIV risk assessmentmodelingMSM deferralsexual partnertransfusion

Identifiers

PMID38864291
PMCPMC11328673

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.