Evidence map›Paper›PMID 38864050›Full record

ArticleCureus2024

Vision Loss as a Presenting Symptom of Vitamin B12 Deficiency.

Izzati Othman, Evelyn Tai, Sangeeta Kuganasan, Norlelawati Abu

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Vitamins and nutraceuticals in glaucoma research.European journal of ophthalmology · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Izzati OthmanDepartment of Ophthalmology, Hospital Tuanku Jaafar Seremban, Negeri Sembilan, MYS.
Evelyn TaiDepartment of Ophthalmology and Visual Science, Hospital Universiti Sains Malaysia, Kubang Kerian, MYS.
Sangeeta KuganasanDepartment of Ophthalmology, Hospital Tuanku Jaafar Seremban, Negeri Sembilan, MYS.
Norlelawati AbuDepartment of Ophthalmology, Hospital Tuanku Jaafar Seremban, Negeri Sembilan, MYS.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nutritional optic neuropathy is a rare and often overlooked factor leading to bilateral, symmetrical, and gradual visual impairment. This condition falls within the category of metabolic neuropathies. We documented a case involving bilateral nutritional optic neuropathy attributed to pancytopenia associated with vitamin B12 deficiency. A healthy 65-year-old Indian woman reported a bilateral, progressive, painless decline in vision over the past six months. She had a history of reduced oral intake for the preceding year and denied experiencing any gastrointestinal or constitutional symptoms. Bilateral visual acuity was 1/60. Examination revealed pale optic discs with attenuated vessels in both eyes and a cup-disc ratio of 0.3. The blood analysis showed low indices and a deficiency in serum vitamin B12. Despite undergoing treatment, her vision remained impaired due to the chronic nature of the condition. This case highlights the importance of identifying visual symptoms in an elderly woman experiencing malnutrition caused by inadequate dietary habits, which leads to bilateral nutritional optic neuropathy.

Indexed as

malnutrition riskmetabolic optic neuropathynutritional blindnessvitamin b12 deficiencyvitamin b supplementation

Identifiers

PMID38864050
PMCPMC11164691

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.