ArticleFrontiers in public health2024
Associations between peak expiratory flow and frailty in olderly individuals: findings from the China health and retirement longitudinal study.
Article in Frontiers in public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Sex modifies the association between blood pressure variability and lung function decline among population over 45 years old: a pooled analysis of two national cohorts.Journal of thoracic disease · 2026Article
- A Prediction Model for 9-Year Depression Risk Among Patients With COPD in China.Depression and anxiety · 2026Article
- Peak Expiratory Flow and Its Trajectories Associated With Frailty in Older Adults: A Prospective Cohort Study.Journal of cachexia, sarcopenia and muscle · 2025Article
- The association between lung function and sensory impairments among chinese middle-aged and older adults: a longitudinal cohort study from CHARLS.NPJ primary care respiratory medicine · 2025Article
- The association between abdominal obesity and pulmonary function trajectories among patients with COPD.Scientific reports · 2025Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Peak Expiratory Flow (PEF) is associated with a variety of adverse health outcomes in older adults; however, the relationship between PEF and frailty remains uncertain, and this study investigated the relationship between PEF and frailty within an olderly Asian demographic. Methods: Data were sourced from the Chinese Health and Retirement Longitudinal Study (CHARLS). Individuals in the study, all 60 years or older, underwent baseline PEF assessments quantified as standardized residual (SR) percentile values. The evaluation of frailty was conducted based on the criteria established by Fried. Participants without frailty at the outset were tracked over a four-year period, during which the relationships between PEF and frailty were examined through logistic regression and discrete-time Cox regression analyses. Results: Among 5,060 participants, cross-sectional analysis revealed that the prevalence of frailty was 2-3 times higher in the lower 10-49th and < 10th SR percentile groups compared to the 80-100th SR percentile group. The longitudinal study corroborated these results, showing an adjusted hazard ratio (HR) of 2.01 (95% CI, 1.15-3.51) for PEF SR percentiles below the 10th, in contrast to those between the 80th and 100th percentiles. Conclusion: PEF independently predicts and determines frailty in older adults. Declines in PEF greater than expected are associated with the development of frailty. Subsequent studies are encouraged to delve deeper into the connection between respiratory function and frailty in diverse contexts.
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