Evidence map›Paper›PMID 38863997›Full record

ArticleJournal of hepatocellular carcinoma2024

Development and Validation of a Novel Prognostic Nomogram Based on Platelet and CD8

Wanxin Shi, Huiwen Yan, Xiaoli Liu, Lihua Yu, Yuqing Xie, Yuan Wu, Yuling Liang, Zhiyun Yang

Abstract read
In one paragraph

Article in Journal of hepatocellular carcinoma, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wanxin Shi *Center of Integrative Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing, People's Republic of China.ORCID 0009-0009-5465-0053
Huiwen Yan *Center of Integrative Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing, People's Republic of China.ORCID 0000-0001-6265-7719
Xiaoli LiuCenter of Integrative Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing, People's Republic of China.
Lihua YuCenter of Integrative Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing, People's Republic of China.ORCID 0000-0002-3228-8286
Yuqing XieCenter of Integrative Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing, People's Republic of China.
Yuan WuCenter of Integrative Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing, People's Republic of China.ORCID 0009-0004-0920-6811
Yuling LiangCenter of Integrative Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing, People's Republic of China.ORCID 0009-0002-1629-0009
Zhiyun YangCenter of Integrative Medicine, Beijing Ditan Hospital, Capital Medical University, Beijing, People's Republic of China.ORCID 0000-0002-1522-0749

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Portal vein tumor thrombosis (PVTT) is one of the hallmarks of advanced Hepatocellular carcinoma (HCC). Platelet (PLT) function parameters and CD8 Patients and Methods: This retrospective study collected 932 HCC patients with PVTT from 2007 to 2017 and randomly divided them into a training cohort (n = 656) and a validation cohort (n = 276). We performed multivariable Cox and Elastic-net regression analysis, constructed a nomogram and used Kaplan-Meier survival curves to compare overall survival and progression-free survival rates in different substrata. Relationships between indicators involved were also analyzed. Results: We found tumor number, size, treatment, PLT, γ-glutamyl transferase, alpha-fetoprotein, mean platelet volume, and CD8 Conclusion: We established a well-performing prognostic model for PVTT based on platelet functional parameters and CD8

Indexed as

CD8+T cells countscorrelation analysishepatocellular carcinomaplateletportal vein tumor thrombusprognostic model

Identifiers

PMID38863997
PMCPMC11166160

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.