Evidence map›Paper›PMID 38863821›Full record

ArticleRSC advances2024

Ursolic acid inhibits NF-κB signaling and attenuates MMP-9/TIMP-1 in progressive osteoarthritis: a network pharmacology-based analysis.

Eman Maher Zahran, Soad A Mohamad, Mohamed M Elsayed, Mohamed Hisham, Sherif A Maher, Usama Ramadan Abdelmohsen, Mahmoud Elrehany, Samar Yehia Desoukey, Mohamed Salah Kamel

Abstract read
In one paragraph

Article in RSC advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. The Application Prospects and Future Outlook ofDrug design, development and therapy · 2026
    Review
  6. Sustainable MnOPharmaceuticals (Basel, Switzerland) · 2025
    Article
  7. Evaluating the Anti-Inflammatory and Chondroprotective Effects ofInternational journal of molecular sciences · 2025
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Eman Maher ZahranDepartment of Pharmacognosy, Faculty of Pharmacy, Deraya University Universities Zone New Minia City 61111 Egypt emanzahran84@yahoo.com eman.maher@deraya.edu.eg.ORCID https://orcid.org/0000-0002-5517-082X
Soad A MohamadDepartment of Pharmaceutics and Clinical Pharmacy, Faculty of Pharmacy, Deraya University Universities Zone New Minia City 61111 Egypt.
Mohamed M ElsayedFaculty of Pharmacy, Deraya University Universities Zone New Minia City 61111 Egypt.
Mohamed HishamDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Deraya University Universities Zone New Minia City 61111 Egypt.
Sherif A MaherDepartment of Biochemistry, Faculty of Pharmacy, New Valley University New Valley Elkharga 71511 Egypt.
Usama Ramadan AbdelmohsenDepartment of Pharmacognosy, Faculty of Pharmacy, Deraya University Universities Zone New Minia City 61111 Egypt emanzahran84@yahoo.com eman.maher@deraya.edu.eg.ORCID https://orcid.org/0000-0002-1014-6922
Mahmoud ElrehanyDepartment of Biochemistry, Faculty of Pharmacy, Deraya University Universities Zone New Minia City 61111 Egypt.
Samar Yehia DesoukeyDepartment of Pharmacognosy, Faculty of Pharmacy, Minia University 61519 Minia Egypt.
Mohamed Salah KamelDepartment of Pharmacognosy, Faculty of Pharmacy, Minia University 61519 Minia Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoarthritis (OA) is a degenerative joint disease, characterized by infiltration of monocytes into the synovial joint which promotes inflammation, stiffness, joint swelling, cartilage degradation and further bone destruction. The leaves of

Identifiers

PMID38863821
PMCPMC11165403

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.