Evidence map›Paper›PMID 38863774›Full record

ArticleCureus2024

Follicle-Stimulating Hormone Receptor (FSHR) Ser680Asn Genotype Does Not Affect the Follicular Fluid Hormonal Profile in Stimulated Cycles Using Different Gonadotropin Preparations for Ovulation Induction: A Pilot Study.

Myrto-Sotiria Papamentzelopoulou, Despoina Mavrogianni, Emmanouela Liokari, Sofoklis Stavros, Anastasios Potiris, Dimitris Doumplis, Dimitrios Loutradis

Abstract read
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In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Myrto-Sotiria Papamentzelopoulou1st Department of Obstetrics and Gynecology, Alexandra General Hospital, National and Kapodistrian University of Athens School of Medicine, Athens, GRC.
Despoina Mavrogianni1st Department of Obstetrics and Gynecology, Alexandra General Hospital, National and Kapodistrian University of Athens School of Medicine, Athens, GRC.
Emmanouela LiokariDepartment of Obstetrics and Gynecology, Fertility Institute, Athens, GRC.
Sofoklis Stavros3rd Department of Obstetrics and Gynecology, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, GRC.
Anastasios Potiris3rd Department of Obstetrics and Gynecology, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, GRC.
Dimitris DoumplisDepartment of Obstetrics and Gynecology, Fertility Institute, Athens, GRC.
Dimitrios LoutradisDepartment of Obstetrics and Gynecology, National and Kapodistrian University of Athens, Athens, GRC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe existing literature lacks consensus on the effectiveness of utilizing polymorphisms to enhance outcomes in in vitro fertilization (IVF), particularly regarding ovulation induction protocols, oocyte and embryo quality, and pregnancy rates. Therefore, the present pilot study aims to assess whether the composition of different gonadotropin preparations affects the ovarian stimulation protocol concerning follicle-stimulating hormone receptor ( METHODOLOGY: A total of 94 IVF patients underwent treatment using a GnRH antagonist protocol with four distinct gonadotropin preparations: HMG, HMG/hCG, rFSH, and rFSH/hCG. Follicular fluid (FF) samples were pooled for each patient for analysis.

resultsNo statistical differences in the FF hormonal profile (progesterone, testosterone, androstenedione, estradiol, FSH, hCG) among the

conclusionsFF hormonal analysis of women undergoing IVF using different ovulation induction protocols and carrying either Ser/Ser, Ser/Asn, or Asn/Asn genotype revealed no significant correlations, in terms of maturation rate of MII oocytes, embryo quality, and pregnancy rate, indicating that the

Indexed as

embryo qualityfollicular fluidfshr ser680asn genotypehormonal profilematuration rateovulation inductionpregnancy rate

Identifiers

PMID38863774
PMCPMC11165288

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.