Evidence map›Paper›PMID 38863744›Full record

ArticleFood & nutrition research2024

A randomized double blind placebo controlled trial to assess the safety and efficacy of a patented fenugreek (

Rajinder Singh Gupta, Amarjit Singh Grover, Pawan Kumar, Apurva Goel, Samudra P Banik, Sanjoy Chakraborty, Mehul Rungta, Manashi Bagchi, Partha Pal, Debasis Bagchi

Abstract read
In one paragraph

Article in Food & nutrition research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. The Effect of Fenugreek (Health science reports · 2026
    Review
  4. Article
  5. Review
  6. Frontiers in pharmacology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rajinder Singh GuptaDepartment of Medicine, Gian Sagar Medical College & Hospital, Banur, Patiala, India.
Amarjit Singh GroverDepartment of Surgery, Gian Sagar Medical College & Hospital, Banur, Patiala, India.
Pawan KumarR&D Department, Chemical Resources (CHERESO), Panchkula, Haryana, India.ORCID https://orcid.org/0000-0002-2822-8133
Apurva GoelRegulatory Department, Chemical Resources (CHERESO), Panchkula, Haryana, India.ORCID https://orcid.org/0000-0003-2909-4226
Samudra P BanikDepartment of Microbiology, Maulana Azad College, Kolkata, India.ORCID https://orcid.org/0000-0003-0075-7508
Sanjoy ChakrabortyDepartment of Biological Sciences, New York City College of Technology/CUNY, Brooklyn, NY, USA.ORCID https://orcid.org/0000-0002-6213-5483
Mehul RungtaR&D Department, Chemical Resources (CHERESO), Panchkula, Haryana, India.ORCID https://orcid.org/0000-0002-4969-0394
Manashi BagchiDepartment of R&D, Dr. Herbs LLC, Concord, CA, USA.ORCID https://orcid.org/0000-0002-1527-6419
Partha PalDepartment of Statistics, Maulana Azad College, Kolkata, India.
Debasis BagchiDepartment of Biology, College of Arts and Sciences, and Department of Psychology, Gordon F. Derner School of Psychology, Adelphi University, Garden City, NY, USA.ORCID https://orcid.org/0000-0001-9478-6427

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Fenugreek plant ( Objective: A placebo-controlled clinical compliance study was designed to assess the effects of complementing Fenfuro Study methodology and trial design: In a randomized double-blind, placebo-controlled trial, 42 individuals (21 male and 21 female volunteers) in the treatment group (out of 57 enrolled) and 39 individuals (17 male and 22 female volunteers) in the placebo group (out of 47 enrolled), all on antidiabetic therapy with Metformin/Metformin with sulphonyl urea within the age group of 18-65 years were administered either 1,000 mg (500 mg × 2) (Fenfuro Results: After 12 weeks of administration, both fasting as well as postprandial serum glucose levels decreased by 38 and 44% respectively in the treatment group. Simultaneously, a significant reduction in glycated hemoglobin by about 34.7% was also noted. The formulation did not have any adverse effect on the study subjects as there was no significant change in C- peptide level and TSH level; liver, kidney, and cardiovascular function was also found to be normal as assessed by serum levels of key immunohematological parameters. No adverse events were reported. Conclusion: This clinical compliance study re-instated and established the safety and efficacy of Fenfuro

Indexed as

Antihyperglycemic therapeuticClinical InvestigationFasting GlucoseFenugreek (Trigonella foenum-graecum) seedsHbA1cPost-Prandial GlucoseT2D

Identifiers

PMID38863744
PMCPMC11165257

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.