Evidence map›Paper›PMID 38863591›Full record

ArticleFrontiers in nutrition2024

Efficacy of a new immunonutrition formula with extra virgin olive oil in the reduction of complications in surgeries of upper digestive tract tumors.

Rocío Villar-Taibo, Alfonso Vidal-Casariego, Alicia Santamaría-Nieto, Ana Cantón-Blanco, Ana B Crujeiras, Gloria Lugo Rodríguez, Gemma Rodríguez-Carnero, Francisco Pita Gutiérrez, Antía Fernández Pombo, Everardo Díaz-López and 4 more

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Rocío Villar-TaiboDepartment of Endocrinology and Nutrition, Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, Spain.
Alfonso Vidal-CasariegoDepartment of Endocrinology and Nutrition, Complejo Hospitalario Universitario de A Coruña, A Coruña, Spain.
Alicia Santamaría-NietoDepartment of Endocrinology and Nutrition, Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, Spain.
Ana Cantón-BlancoDepartment of Endocrinology and Nutrition, Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, Spain.
Ana B CrujeirasEpigenomics in Endocrinology and Nutrition Group, Epigenomics Unit, Instituto de Investigación Sanitaria de Santiago (IDIS), Complejo Hospitalario Universitario de Santiago (CHUS/SERGAS), Santiago de Compostela, Spain.
Gloria Lugo RodríguezDepartment of Endocrinology and Nutrition, Complejo Hospitalario Universitario de A Coruña, A Coruña, Spain.
Gemma Rodríguez-CarneroDepartment of Endocrinology and Nutrition, Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, Spain.
Francisco Pita GutiérrezDepartment of Endocrinology and Nutrition, Complejo Hospitalario Universitario de A Coruña, A Coruña, Spain.
Antía Fernández PomboDepartment of Endocrinology and Nutrition, Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, Spain.
Everardo Díaz-LópezDepartment of Endocrinology and Nutrition, Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, Spain.
Andrea Román EyoDepartment of Endocrinology and Nutrition, Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, Spain.
Uxía Rodríguez LavandeiraDepartment of Endocrinology and Nutrition, Complejo Hospitalario Universitario de A Coruña, A Coruña, Spain.
Alberto Pena-DubraDepartment of Endocrinology and Nutrition, Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, Spain.
Miguel Ángel Martínez-OlmosDepartment of Endocrinology and Nutrition, Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: To demonstrate whether a nutritional supplement enriched with arginine, nucleotides, omega-3 fatty acids, and extra virgin olive oil reduces postoperative complications in patients with tumors in the upper digestive tract. Methods: A randomized, controlled, double-blind, multicenter clinical trial, in which a new immunomodulatory formula with extra virgin olive oil was compared with a standard isoprotein and isoenergetic formula. Patients with gastric, esophageal or biliopancreatic tumors were recruited to receive two units of immunomodulatory formula or control, 5 days before the surgical intervention. Results: A total of 119 patients were recruited. There was a significant reduction in the number of reinterventions (7.7 vs. 20.4%; Conclusion: The immunomodulatory formula with extra virgin olive oil administered 5 days before surgery for stomach, esophageal and biliopancreatic tumors improved cellular health and reduced postoperative complications.

Indexed as

argininecancerextra virgin olive oilimmunonutritionomega-3 fatty acidssurgery

Identifiers

PMID38863591
PMCPMC11165349

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.