Evidence map›Paper›PMID 38863572›Full record

ArticleBrain communications2024

Converging peripheral blood microRNA profiles in Parkinson's disease and progressive supranuclear palsy.

Lukas Pavelka, Armin Rauschenberger, Ahmed Hemedan, Marek Ostaszewski, Enrico Glaab, Rejko Krüger, NCER-PD Consortium

Abstract read
In one paragraph

Article in Brain communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. The Role of MicroRNAs in Progressive Supranuclear Palsy-A Systematic Review.International journal of molecular sciences · 2024
    Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lukas PavelkaTransversal Translational Medicine, Luxembourg Institute of Health (LIH), Strassen L-1445, Luxembourg.ORCID https://orcid.org/0000-0002-7721-3317
Armin RauschenbergerBiomedical Data Science Group, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-sur-Alzette L-4367, Luxembourg.ORCID https://orcid.org/0000-0001-6498-4801
Ahmed HemedanBioinformatics Core Unit, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-sur-Alzette L-4367, Luxembourg.
Marek OstaszewskiBioinformatics Core Unit, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-sur-Alzette L-4367, Luxembourg.ORCID https://orcid.org/0000-0003-1473-370X
Enrico GlaabBiomedical Data Science Group, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Esch-sur-Alzette L-4367, Luxembourg.ORCID https://orcid.org/0000-0003-3977-7469
Rejko KrügerTransversal Translational Medicine, Luxembourg Institute of Health (LIH), Strassen L-1445, Luxembourg.
NCER-PD Consortium

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs act via targeted suppression of messenger RNA translation in the DNA-RNA-protein axis. The dysregulation of microRNA(s) reflects the epigenetic changes affecting the cellular processes in multiple disorders. To understand the complex effect of dysregulated microRNAs linked to neurodegeneration, we performed a cross-sectional microRNA expression analysis in idiopathic Parkinson's disease (

Indexed as

Boolean modellingmicroRNAnatural killer cellParkinson's diseaseprogressive supranuclear palsy

Identifiers

PMID38863572
PMCPMC11166179

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.