Evidence map›Paper›PMID 38863478›Full record

ArticleIn silico pharmacology2024

In silico bioprospecting of receptors associated with the mechanism of action of Rondonin, an antifungal peptide from spider

Elias Jorge Muniz Seif, Marcelo Yudi Icimoto, Pedro Ismael Silva Júnior

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in In silico pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Elias Jorge Muniz SeifPostgraduate Program of Molecular Biology, Biophysics and Biochemistry Department, Federal University of São Paulo, São Paulo, São Paulo 04021-001 Brazil.
Marcelo Yudi IcimotoBiophysics Department, Federal University of São Paulo, São Paulo, São Paulo 04024-002 Brazil.
Pedro Ismael Silva JúniorPostgraduate Program of Molecular Biology, Biophysics and Biochemistry Department, Federal University of São Paulo, São Paulo, São Paulo 04021-001 Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple drug-resistant fungal species are associated with the development of diseases. Thus, more efficient drugs for the treatment of these aetiological agents are needed. Rondonin is a peptide isolated from the haemolymph of the spider Supplementary Information: The online version contains supplementary material available at 10.1007/s40203-024-00224-1.

Indexed as

AntimicrobialComputational biologyDynamic simulationLigand binding sitesMolecular target

Identifiers

PMID38863478
PMCPMC11162988

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.