Evidence map›Paper›PMID 38863310›Full record

ArticleJournal of applied clinical medical physics2024

What is the optimal isodose line for stereotactic radiotherapy for single brain metastases using HyperArc?

Tomohiro Sagawa, Toshiki Ikawa, Shingo Ohira, Naoyuki Kanayama, Yoshihiro Ueda, Shoki Inui, Masayoshi Miyazaki, Koji Konishi

Abstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tomohiro SagawaDepartment of Radiation Oncology, Osaka International Cancer Institute, Osaka, Japan.ORCID https://orcid.org/0000-0002-3768-3437
Toshiki IkawaDepartment of Radiation Oncology, Osaka International Cancer Institute, Osaka, Japan.ORCID https://orcid.org/0000-0001-9097-0227
Shingo OhiraDepartment of Radiation Oncology, Osaka International Cancer Institute, Osaka, Japan.
Naoyuki KanayamaDepartment of Radiation Oncology, Osaka International Cancer Institute, Osaka, Japan.ORCID https://orcid.org/0000-0003-0016-2213
Yoshihiro UedaDepartment of Radiation Oncology, Osaka International Cancer Institute, Osaka, Japan.
Shoki InuiDepartment of Radiation Oncology, Osaka International Cancer Institute, Osaka, Japan.ORCID https://orcid.org/0000-0002-5691-8457
Masayoshi MiyazakiDepartment of Radiation Oncology, Osaka International Cancer Institute, Osaka, Japan.
Koji KonishiDepartment of Radiation Oncology, Osaka International Cancer Institute, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe study aimed to investigate the optimal isodose line (IDL) in linear accelerator-based stereotactic radiotherapy for single brain metastasis, using HyperArc. We compared the dosimetric parameters for target and normal brain tissue among six plans with different IDLs.

methodsThis study included 30 patients with single brain metastasis. We retrospectively generated six plans for each tumor with different IDLs (80%, 70%, 60%, 50%, 40%, and 33%) using HyperArc. All treatment plans were normalized to the prescription dose of 35 Gy in five fractions which was covered by 95% of the planning target volume (PTV), defined by adding a 1.0 mm margin to the gross tumor volume (GTV). The dosimetric parameters were compared among the six plans.

resultsFor GTV > 0.1 cm

conclusionThe optimal IDL is 40%-50% for GTV > 0.1 cm

Indexed as

Brain NeoplasmsOrgans at RiskRadiosurgeryRadiotherapy DosageRadiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedAgedFemaleHumansMaleMiddle AgedParticle AcceleratorsPrognosisRetrospective Studiesbrain metastasesHyperArcisodose linestereotactic radiotherapytreatment planning

Identifiers

PMID38863310
PMCPMC11492347

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.