Evidence map›Paper›PMID 38863151›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2024

Enlarged perivascular spaces in the basal ganglia are associated with arteries not veins.

Jan Oltmer, Hendrik Mattern, Julia Beck, Renat Yakupov, Steven M Greenberg, Jaco Jm Zwanenburg, Tine Arts, Emrah Düzel, Susanne J van Veluw, Stefanie Schreiber and 1 more

Abstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Review
  7. MRI markers of cerebrospinal fluid dynamics predict dementia and mediate the impact of cardiovascular risk.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jan OltmerAthinoula A. Martinos Center, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, USA.ORCID 0000-0001-6190-7069
Hendrik MatternGerman Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.
Julia BeckDepartment of Neurology, Otto-Von-Guericke University, Magdeburg, Germany.
Renat YakupovGerman Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.
Steven M GreenbergJ. Philip Kistler Stroke Research Center, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Jaco Jm ZwanenburgCenter for Image Sciences, University Medical Center Utrecht, Utrecht, Netherlands.ORCID 0000-0002-4282-5719
Tine ArtsCenter for Image Sciences, University Medical Center Utrecht, Utrecht, Netherlands.
Emrah DüzelGerman Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.
Susanne J van VeluwJ. Philip Kistler Stroke Research Center, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-7957-8643
Stefanie SchreiberGerman Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.
Valentina PerosaGerman Center for Neurodegenerative Diseases (DZNE), Magdeburg, Germany.

Funding

Unraveling the mechanisms of microhemorrhages in cerebral amyloid angiopathyR00AG059893 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI VAN VELUW, SUSANNE JANNEKE · 2020 to 2022
$745k
Unraveling the mechanisms of microhemorrhages in cerebral amyloid angiopathy; from ex vivo MRI in humans to in vivo optics in miceK99AG059893 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI VAN VELUW, SUSANNE JANNEKE · 2018 to 2019
$273k
NIA NIH HHS K99 AG059893NIA NIH HHS R00 AG059893
6 · The paper itself

Abstract

Enlarged perivascular spaces (EPVS) are common in cerebral small vessel disease (CSVD) and have been identified as a marker of dysfunctional brain clearance. However, it remains unknown if the enlargement occurs predominantly around arteries or veins. We combined

Indexed as

Basal GangliaCerebral Small Vessel DiseasesGlymphatic SystemMagnetic Resonance ImagingAgedAged, 80 and overBlood Flow VelocityCerebral ArteriesCerebral VeinsCerebrovascular CirculationFemaleHumansMaleMiddle Aged7T MRIcerebral small vessel diseasehistopathologyhypertensive arteriopathyperivascular clearance

Identifiers

PMID38863151
PMCPMC11542128

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.