Evidence map›Paper›PMID 38862884›Full record

ArticleBMC medical imaging2024

Artificial intelligence-driven computer aided diagnosis system provides similar diagnosis value compared with doctors' evaluation in lung cancer screening.

Shan Gao, Zexuan Xu, Wanli Kang, Xinna Lv, Naihui Chu, Shaofa Xu, Dailun Hou

Abstract readComparative Study
In one paragraph

Article in BMC medical imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shan Gao *Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing, China.
Zexuan Xu *Beijing Chest Hospital, Capital Medical University, Beijing, China.
Wanli KangBeijing Chest Hospital, Capital Medical University, Beijing, China.
Xinna LvBeijing Chest Hospital, Capital Medical University, Beijing, China.
Naihui ChuBeijing Tuberculosis and Thoracic Tumor Research Institute, Beijing, China. dongchu1994@sina.com.
Shaofa XuBeijing Chest Hospital, Capital Medical University, Beijing, China. xushaofa@263.net.
Dailun HouBeijing Chest Hospital, Capital Medical University, Beijing, China. hou.dl@mail.ccmu.edu.cn.

Funding

Beijing Science and Technology Planning Project Z151100002115049
6 · The paper itself

Abstract

objectiveTo evaluate the consistency between doctors and artificial intelligence (AI) software in analysing and diagnosing pulmonary nodules, and assess whether the characteristics of pulmonary nodules derived from the two methods are consistent for the interpretation of carcinomatous nodules. MATERIALS AND

methodsThis retrospective study analysed participants aged 40-74 in the local area from 2011 to 2013. Pulmonary nodules were examined radiologically using a low-dose chest CT scan, evaluated by an expert panel of doctors in radiology, oncology, and thoracic departments, as well as a computer-aided diagnostic(CAD) system based on the three-dimensional(3D) convolutional neural network (CNN) with DenseNet architecture(InferRead CT Lung, IRCL). Consistency tests were employed to assess the uniformity of the radiological characteristics of the pulmonary nodules. The receiver operating characteristic (ROC) curve was used to evaluate the diagnostic accuracy. Logistic regression analysis is utilized to determine whether the two methods yield the same predictive factors for cancerous nodules.

resultsA total of 570 subjects were included in this retrospective study. The AI software demonstrated high consistency with the panel's evaluation in determining the position and diameter of the pulmonary nodules (kappa = 0.883, concordance correlation coefficient (CCC) = 0.809, p = 0.000). The comparison of the solid nodules' attenuation characteristics also showed acceptable consistency (kappa = 0.503). In patients diagnosed with lung cancer, the area under the curve (AUC) for the panel and AI were 0.873 (95%CI: 0.829-0.909) and 0.921 (95%CI: 0.884-0.949), respectively. However, there was no significant difference (p = 0.0950). The maximum diameter, solid nodules, subsolid nodules were the crucial factors for interpreting carcinomatous nodules in the analysis of expert panel and IRCL pulmonary nodule characteristics.

conclusionAI software can assist doctors in diagnosing nodules and is consistent with doctors' evaluations and diagnosis of pulmonary nodules.

Indexed as

Artificial IntelligenceDiagnosis, Computer-AssistedLung NeoplasmsTomography, X-Ray ComputedAdultAgedEarly Detection of CancerFemaleHumansMaleMiddle AgedNeural Networks, ComputerRadiographic Image Interpretation, Computer-AssistedRetrospective StudiesROC CurveSoftwareArtificial IntelligenceComputed TomographyDiagnosisLung cancerPulmonary nodule

Identifiers

PMID38862884
PMCPMC11165751

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.