Evidence map›Paper›PMID 38862869›Full record

ArticleBreast cancer (Tokyo, Japan)2024

Delayed breast reconstruction with autologous free flap after radiation therapy: vascular complications and aesthetic outcomes.

Kimie Miyazawa, Toshihiko Satake, Mayu Muto, Yui Tsunoda, Tomoyuki Koike, Kazutaka Narui, Ryohei Katsuragi, Satoshi Onoda, Takashi Ishikawa

Abstract read
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In one paragraph

Article in Breast cancer (Tokyo, Japan), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Simultaneous Bilateral Microsurgery in Autologous Tissue Breast Reconstruction.Plastic and reconstructive surgery. Global open · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kimie MiyazawaDepartment of Plastic Surgery, Nagano Matsushiro General Hospital, Nagano, Japan.
Toshihiko SatakeDepartment of Plastic, Reconstructive, and Aesthetic Surgery, Faculty of Medicine, University of Toyama, Toyama, Japan. toshi@med.u-toyama.ac.jp.ORCID http://orcid.org/0000-0002-4122-628X
Mayu MutoDepartment of Plastic and Reconstructive Surgery, Yokohama City University Medical Center, Yokohama, Japan.
Yui TsunodaDepartment of Plastic and Reconstructive Surgery, Yokohama City University Medical Center, Yokohama, Japan.
Tomoyuki KoikeDepartment of Plastic and Reconstructive Surgery, Yokohama City University Medical Center, Yokohama, Japan.
Kazutaka NaruiDepartment of Breast and Thyroid Surgery, Yokohama City University Medical Center, Yokohama, Japan.
Ryohei KatsuragiDepartment of Plastic, Reconstructive, and Aesthetic Surgery, Faculty of Medicine, University of Toyama, Toyama, Japan.
Satoshi OnodaDepartment of Plastic, Reconstructive, and Aesthetic Surgery, Faculty of Medicine, University of Toyama, Toyama, Japan.
Takashi IshikawaDepartment of Breast Oncology and Surgery, Tokyo Medical University, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe safety and outcome of breast reconstruction after radiotherapy are controversial, and the aesthetic aspects have not been studied extensively. We compared the results of vascular anastomosis, the incidence of postoperative complications, and aesthetic appearance between patients who had and had not received radiotherapy who then had undergone delayed breast reconstruction with autologous free flaps from the abdomen, thighs, and buttocks.

methodsIn total, 257 flaps in 241 patients were investigated; 194 and 63 flaps implanted in patients who did not receive radiotherapy and who received radiotherapy before breast reconstruction, respectively. Of the 257 flaps, 221, 20, 14, and 2 came from the abdomen, thighs, buttocks, and other anatomic locations, respectively. We evaluated aesthetic outcomes in 105 patients who had not received radiotherapy and 35 who had.

resultsWe found no significant differences between the two groups in the incidence of vascular reanastomosis, the time required for anastomosis, or the incidence of unplanned reoperation. Complications such as flap necrosis were rare in both groups. Aesthetic outcomes were significantly better in the patients who had not received radiotherapy.

conclusionsBreast reconstruction with autologous free flaps can be performed safely in patients who have received radiotherapy, but the aesthetic result is slightly inferior to that in patients who had not received radiotherapy.

Indexed as

Breast NeoplasmsFree Tissue FlapsMammaplastyPostoperative ComplicationsAdultAgedEstheticsFemaleHumansMastectomyMiddle AgedRadiotherapy, AdjuvantRetrospective StudiesTransplantation, AutologousTreatment OutcomeAesthetic outcomeDelayed breast reconstructionFree autologous flapRadiation therapyVascular complication

Identifiers

PMID38862869

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.