Evidence map›Paper›PMID 38862806›Full record

ArticleLasers in medical science2024

Diagnostic ability of the combination of retinal microvasculature evaluation and static automated perimetry for early primary open-angle glaucoma.

Shushu Xu, Zhongjing Lin, Yanzhi Guo, Ping Huang, Shouyue Huang, Yisheng Zhong

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Article in Lasers in medical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shushu XuDepartment of Ophthalmology, Ruijin Hospital Affiliated Medical School, Shanghai Jiaotong University, 197 Ruijin Er Road, Shanghai, 200025, China.
Zhongjing LinDepartment of Ophthalmology, Renji Hospital Affiliated Medical School, Shanghai Jiaotong University, 160 Pujian Road, Shanghai, 200127, China.
Yanzhi GuoDepartment of Ophthalmology, Ruijin Hospital Affiliated Medical School, Shanghai Jiaotong University, 197 Ruijin Er Road, Shanghai, 200025, China.
Ping HuangShanghai Key Laboratory for Bone and Joint Diseases, Ruijin Hospital Affiliated Medical School, Shanghai Institute of Traumatology and Orthopaedics, Shanghai Jiaotong University, 197 Ruijin Er Road, Shanghai, 200025, China.
Shouyue HuangDepartment of Ophthalmology, Ruijin Hospital Affiliated Medical School, Shanghai Jiaotong University, 197 Ruijin Er Road, Shanghai, 200025, China. yachtjj@hotmail.com.
Yisheng ZhongDepartment of Ophthalmology, Ruijin Hospital Affiliated Medical School, Shanghai Jiaotong University, 197 Ruijin Er Road, Shanghai, 200025, China. yszhong68@126.com.

Funding

Shanghai Municipal Population and Family Planning Commission NO. 202140130, NO.2020LP034Shanghai Science and Technology Development Foundation NO. 21Y11909700
6 · The paper itself

Abstract

purposeTo investigate the diagnostic ability of retinal superficial vasculature evaluation by optic coherence tomography angiography (OCTA) combined with visual field (VF) testing for early primary open-angle glaucoma (POAG). PATIENTS AND

methodsIn this cross-sectional study, 84 participants were included, including 11 in the ocular hypertension (OHT) group, 11 in the preperimetric POAG (pre-POAG) group, 29 in the early POAG group and 33 in the control group. All participants underwent 6 × 6 mm

resultsThe superficial retinal vessel densities (VD) in peri-nasal, para-temporal, peri-temporal and peri-inferior regions around the macula, as well as vessel area densities (VAD) in all peripapillary regions, were significantly different among the four groups, with lower VD or VAD in the early POAG patients compared to the normal individuals. The diagnostic ability of peripapillary superficial retinal VAD alone or VF testing alone was limited for early POAG only. However, the combination of these two was more effective in distinguishing normal individuals from OHT subjects or pre-POAG patients without VF defects, with better performance than the combination of peripapillary retinal nerve fiber layer (RNFL) thickness and VF indicators.

conclusionsPeripapillary retinal vessel densities were generally lower in early POAG patients compared to normal individuals. The combination of peripapillary superficial retinal VAD by OCTA with white-on-white VF testing improved the ability to distinguish POAG patients at early stage without function impairment, which may help in providing reference and guidance for the following-up and treatment of suspected POAG patients.

Indexed as

Glaucoma, Open-AngleMicrovesselsRetinal VesselsTomography, Optical CoherenceVisual Field TestsAdultAgedCross-Sectional StudiesEarly DiagnosisFemaleHumansMaleMiddle AgedOptic DiskROC CurveVisual FieldsGlaucomaMicro-circulationOCTAOptic nerve headRNFLVisual field

Identifiers

PMID38862806

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.