ReviewMolecular psychiatry2024
Neuropsychobiology of fear-induced bradycardia in humans: progress and pitfalls.
Review in Molecular psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A Meta-Analysis of the Effects of Early Life Stress on the Prefrontal Cortex Transcriptome Reveals Long-Term Downregulation of Myelin-Related Gene Expression.Brain and behavior · 2025Pooled it
- AdipoRon's Impact on Alzheimer's Disease-A Systematic Review and Meta-Analysis.International journal of molecular sciences · 2025Pooled it
- Nocturnal Risk Assessment and Its Association With Anxiety Symptoms.Psychophysiology · 2026Trial
- How observing others influences the subsequent acquisition of fear of bodily sensations.Journal of mood and anxiety disorders · 2026Article
- Precocial parasympathetic-mediated cardiac regulation in embryonic gulf killifish (Fundulus grandis).The Journal of experimental biology · 2026Article
- Uncovering Heart Rate Response Patterns to Threat Pictures Through Deep Latent Representation Learning with a Variational Autoencoder.Psychophysiology · 2026Article
- A Feasibility Study of Literature-Guided HRV Stratification Using Large Language Models.Diagnostics (Basel, Switzerland) · 2026Article
- Tactile perception and tolerability thresholds of TMS characterized by intensity across locations and frequencies.Clinical neurophysiology practice · 2026Article
- Therapeutic potential of plant-derived exosome-like nanoparticles for CNS diseases: advancements in preparation and characterization.Annals of medicine · 2025Review
- Heart rate response and recovery during exercise and dementia risk: a prospective UK biobank study.Scientific reports · 2025Article
- Pain and mental-health scores significantly different in male and female football-players with traits of decision-reinvestment, but heart-rate-variability differences are unsupported.Scientific reports · 2025Observational
- From Microbial Switches to Metabolic Sensors: Rewiring the Gut-Brain Kynurenine Circuit.Biomedicines · 2025Review
- Gut microbiota and the tryptophan-kynurenine pathway in anxiety: new insights and treatment strategies.Journal of neural transmission (Vienna, Austria : 1996) · 2025Review
- How Orienting and Defence Drives Oscillatory Responses in Human Visual and Motor Cortical Circuits During Viewing of Threat Pictures: Evidence From ssVEPs and Beta-Band Desynchronization.The European journal of neuroscience · 2025Article
- Navigating Neurodegeneration: Integrating Biomarkers, Neuroinflammation, and Imaging in Parkinson's, Alzheimer's, and Motor Neuron Disorders.Biomedicines · 2025Article
- Cardiac history and post-stroke depression association in Chinese stroke survivors: a cross sectional study.Scientific reports · 2025Article
- The Locus Coeruleus: Anatomy, Physiology, and Stress-Related Neuropsychiatric Disorders.The European journal of neuroscience · 2025Review
- Assessing the clinical reliability of short-term heart rate variability: insights from controlled dual-environment and dual-position measurements.Scientific reports · 2025Article
- Cortisol Imbalance and Fear Learning in PTSD: Therapeutic Approaches to Control Abnormal Fear Responses.Current neuropharmacology · 2025Review
- Neurophysiological and cognitive enhancements in autonomous sensory meridian response identified using heart rate variability and electroencephalography connectivity.Frontiers in psychology · 2025Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the last century, the paradigm of fear conditioning has greatly evolved in a variety of scientific fields. The techniques, protocols, and analysis methods now most used have undergone a progressive development, theoretical and technological, improving the quality of scientific productions. Fear-induced bradycardia is among these techniques and represents the temporary deceleration of heart beats in response to negative outcomes. However, it has often been used as a secondary measure to assess defensive responding to threat, along other more popular techniques. In this review, we aim at paving the road for its employment as an additional tool in fear conditioning experiments in humans. After an overview of the studies carried out throughout the last century, we describe more recent evidence up to the most contemporary research insights. Lastly, we provide some guidelines concerning the best practices to adopt in human fear conditioning studies which aim to investigate fear-induced bradycardia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.