Evidence map›Paper›PMID 38862505›Full record

ReviewNature communications2024

Astronaut omics and the impact of space on the human body at scale.

Lindsay A Rutter, Henry Cope, Matthew J MacKay, Raúl Herranz, Saswati Das, Sergey A Ponomarev, Sylvain V Costes, Amber M Paul, Richard Barker, Deanne M Taylor and 5 more

Abstract readReview
In one paragraph

Review in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Science of omics: a molecular space odyssey.Experimental physiology · 2025
    Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Lindsay A Rutter *Transborder Medical Research Center, University of Tsukuba, 305-8575, Tsukuba, Japan.
Henry Cope *School of Medicine, University of Nottingham, Derby, DE22 3DT, UK.ORCID 0000-0002-4984-0567
Matthew J MacKay *Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, 10065, USA.
Raúl HerranzCentro de Investigaciones Biológicas "Margarita Salas" (CSIC), Ramiro de Maeztu 9, Madrid, 28040, Spain.ORCID 0000-0002-0246-9449
Saswati DasDepartment of Biochemistry, Atal Bihari Vajpayee Institute of Medical Sciences & Dr. Ram Manohar Lohia Hospital, New Delhi, 110001, India.
Sergey A PonomarevDepartment of Immunology and Microbiology, Institute for the Biomedical Problems, Russian Academy of Sciences, 123007, Moscow, Russia.ORCID 0000-0002-5364-7815
Sylvain V CostesSpace Biosciences Division, NASA Ames Research Center, Moffett Field, CA, 94035, USA.ORCID 0000-0002-8542-2389
Amber M PaulEmbry-Riddle Aeronautical University, Department of Human Factors and Behavioral Neurobiology, Daytona Beach, FL, 32114, USA.
Richard BarkerDepartment of Botany, University of Wisconsin-Madison, Madison, WI, 53706, USA.
Deanne M TaylorDepartment of Biomedical and Health Informatics, The Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.ORCID 0000-0002-3302-4610
Daniela BezdanInstitute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, 72076, Germany.ORCID 0000-0002-1203-8239
Nathaniel J SzewczykSchool of Medicine, University of Nottingham, Derby, DE22 3DT, UK.ORCID 0000-0003-4425-9746
Masafumi MurataniTransborder Medical Research Center, University of Tsukuba, 305-8575, Tsukuba, Japan.ORCID 0000-0002-0276-8000
Christopher E MasonDepartment of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, 10065, USA. chm2042@med.cornell.edu.ORCID 0000-0002-1850-1642
Stefania GiacomelloSciLifeLab, KTH Royal Institute of Technology, Stockholm, 17165, Sweden. stefania.giacomello@scilifelab.se.ORCID 0000-0003-0738-1574

Funding

The Spatiotemporal Landscape of the Human Brain EpitranscriptomeR01MH117406 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI MASON, CHRISTOPHER EDWARD · 2018 to 2022
$3.3M
NIMH NIH HHS R01 MH117406
6 · The paper itself

Abstract

Future multi-year crewed planetary missions will motivate advances in aerospace nutrition and telehealth. On Earth, the Human Cell Atlas project aims to spatially map all cell types in the human body. Here, we propose that a parallel Human Cell Space Atlas could serve as an openly available, global resource for space life science research. As humanity becomes increasingly spacefaring, high-resolution omics on orbit could permit an advent of precision spaceflight healthcare. Alongside the scientific potential, we consider the complex ethical, cultural, and legal challenges intrinsic to the human space omics discipline, and how philosophical frameworks may benefit from international perspectives.

Indexed as

AstronautsSpace FlightGenomicsHuman BodyHumans

Identifiers

PMID38862505
PMCPMC11166943

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.