Evidence map›Paper›PMID 38862454›Full record

ArticleNan fang yi ke da xue xue bao = Journal of Southern Medical University2024

[Repeated mild traumatic brain injury in the parietal cortex inhibits expressions of NLG-1 and PSD-95 in the medulla oblongata of mice].

M Li, L He, T Li, Y Bao, X Xu, G Chen

Abstract readEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

6 authors.

M LiSchool of Forensic Medicine, Wannan Medical College, Wuhu 241000, China.
L HeSchool of Forensic Medicine, Wannan Medical College, Wuhu 241000, China.
T LiSchool of Forensic Medicine, Wannan Medical College, Wuhu 241000, China.
Y BaoSchool of Forensic Medicine, Wannan Medical College, Wuhu 241000, China.
X XuSchool of Forensic Medicine, Wannan Medical College, Wuhu 241000, China.
G ChenSchool of Forensic Medicine, Wannan Medical College, Wuhu 241000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the effects of repeated mild traumatic brain injury (rmTBI) in the parietal cortex on neuronal morphology and synaptic plasticity in the medulla oblongata of mice.

methodsThirty-two male ICR mice were randomly divided into sham operation group (

resultsNone of the mice in the sham-operated group died, while the mortality rate was 41.67% in rmTBI group. The mice surviving rmTBI showed significantly reduced NSS, delayed recovery of righting reflex, increased immobility time in forced swimming test (

conclusionThe structural and functional anomalies of the synapses in the medulla oblongata may contribute to death and neurological impairment following rmTBI in mice.

Indexed as

Cell Adhesion Molecules, NeuronalDisks Large Homolog 4 ProteinMedulla OblongataMice, Inbred ICRParietal LobeAnimalsBrain Injuries, TraumaticMaleMiceNeuronal PlasticityNeuronsCell Adhesion Molecules, NeuronalDisks Large Homolog 4 ProteinDlg4 protein, mouseneuroligin 1medulla oblongataneuroligin 1postsynaptic density protein 95repeated mild traumatic brain injurysynaptic plasticity

Identifiers

PMID38862454
PMCPMC11166725

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.