Evidence map›Paper›PMID 38862244›Full record

ArticleRMD open2024

Anatomical pattern of entheseal and synovial fibroblast activation in patients with psoriasis and its risk of developing psoriatic arthritis.

Giulia Corte, Armin Atzinger, Selahattin Alp Temiz, Rita Noversa de Sousa, Melek Yalcin Mutlu, Verena Schoenau, Maria Gabriella Raimondo, Arnd Kleyer, Torsten Kuwert, Andreas Ramming and 5 more

Abstract read
In one paragraph

Article in RMD open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Molecular imaging of psoriatic arthritis.Current opinion in rheumatology · 2025
    Review
  10. Article
  11. Unconventional Imaging Methods in Psoriatic Arthritis.Current rheumatology reports · 2025
    Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Giulia CorteDepartment of Internal Medicine 3, Rheumatology and Immunology, Erlangen University Hospital, Erlangen, Germany.
Armin AtzingerDepartment of Nuclear Medicine, Erlangen University Hospital, Erlangen, Germany.
Selahattin Alp TemizDepartment of Internal Medicine 3, Rheumatology and Immunology, Erlangen University Hospital, Erlangen, Germany.ORCID 0000-0003-0804-3198
Rita Noversa de SousaDepartment of Internal Medicine 3, Rheumatology and Immunology, Erlangen University Hospital, Erlangen, Germany.
Melek Yalcin MutluDepartment of Internal Medicine 3, Rheumatology and Immunology, Erlangen University Hospital, Erlangen, Germany.
Verena SchoenauDepartment of Internal Medicine 3, Rheumatology and Immunology, Erlangen University Hospital, Erlangen, Germany.ORCID 0000-0003-0586-9824
Maria Gabriella RaimondoDepartment of Internal Medicine 3, Rheumatology and Immunology, Erlangen University Hospital, Erlangen, Germany.
Arnd KleyerDepartment of Internal Medicine 3, Rheumatology and Immunology, Erlangen University Hospital, Erlangen, Germany.
Torsten KuwertDepartment of Nuclear Medicine, Erlangen University Hospital, Erlangen, Germany.
Andreas RammingDepartment of Internal Medicine 3, Rheumatology and Immunology, Erlangen University Hospital, Erlangen, Germany.
David SimonDepartment of Internal Medicine 3, Rheumatology and Immunology, Erlangen University Hospital, Erlangen, Germany.ORCID 0000-0001-8310-7820
Michael SticherlingDeutsches Zentrum fuer Immuntherapie (DZI), Erlangen University Hospital, Erlangen, Germany.
Christian SchmidkonzDepartment of Nuclear Medicine, Erlangen University Hospital, Erlangen, Germany.
Georg SchettDepartment of Internal Medicine 3, Rheumatology and Immunology, Erlangen University Hospital, Erlangen, Germany.
Filippo FagniDepartment of Internal Medicine 3, Rheumatology and Immunology, Erlangen University Hospital, Erlangen, Germany Filippo.Fagni@uk-erlangen.de.ORCID 0000-0002-6122-0774

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess the presence and anatomical distribution of activated fibroblasts in the joints and entheses of patients with psoriasis with arthralgia and to test how fibroblast activation visualised by

methodsWe conducted a prospective cohort study in patients with psoriasis and arthralgia who underwent clinical and ultrasound evaluation and whole-body PET/CT imaging with

results36 patients with psoriasis were enrolled.

conclusionsPatients with psoriasis presenting with arthralgia show localised signs of resident tissue activation in joints and entheses, which are associated with higher risk of developing PsA.

Indexed as

Arthritis, PsoriaticFibroblastsPositron Emission Tomography Computed TomographyPsoriasisAdultAgedDisease ProgressionFemaleHumansMaleMiddle AgedProspective StudiesSynovial MembraneUltrasonographyFibroblastsOutcome Assessment, Health CarePsoriatic ArthritisRisk FactorsUltrasonography

Identifiers

PMID38862244
PMCPMC11168197

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.