Evidence map›Paper›PMID 38861995›Full record

ArticlePhysics in medicine and biology2024

Investigation of intra-fractionated range guided adaptive proton therapy (RGAPT): II. Range-shift compensated on-line treatment adaptation and verification.

Mingli Chen, Dongxu Yang, Xiaorong R Zhu, Lin Ma, David R Grosshans, Yiping Shao, Weiguo Lu

Abstract read
In one paragraph

Article in Physics in medicine and biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mingli ChenDepartment of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390, United States of America.ORCID 0000-0002-9758-3788
Dongxu YangDepartment of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390, United States of America.
Xiaorong R ZhuDepartment of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, TX 77030, United States of America.
Lin MaDepartment of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390, United States of America.ORCID 0000-0002-5637-8577
David R GrosshansDepartment of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, United States of America.
Yiping ShaoDepartment of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390, United States of America.ORCID 0000-0002-3678-8341
Weiguo LuDepartment of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390, United States of America.ORCID 0000-0003-3036-7287

Funding

Novel On-line PET Based Intra-Beam Range Verification and Delivery Optimization for Improved Particle Radiation TherapyR01CA218402 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI LU, WEIGUO, SHAO, YIPING · 2018 to 2022
$2.2M
High-Precision Proton Therapy for Liver Cancer: Developing an End-to-end Strategy with Real-time Liver Tumor Localization and On-the-fly Plan Delivery AdaptationR01CA280135 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI Weiguo Lu, You Zhang · 2024 to 2026
$1.8M
NCI NIH HHS R01 CA218402NCI NIH HHS R01 CA280135
6 · The paper itself

Abstract

We previously proposed range-guided adaptive proton therapy (RGAPT) that uses mid-range treatment beams as probing beams and intra-fractionated range measurements for online adaptation. In this work, we demonstrated experimental verification and reported the dosimetric accuracy for RGAPT. A STEEV phantom was used for the experiments, and a 3 × 3 × 3 cm

Indexed as

Phantoms, ImagingProton TherapyRadiotherapy Planning, Computer-AssistedDose Fractionation, RadiationHumansRadiometryRadiotherapy, Image-Guidedproton beam rangerange guided adaptive proton therapyRGAPT

Identifiers

PMID38861995
PMCPMC13007004

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.