Evidence map›Paper›PMID 38861707›Full record

Trial reportJMIR human factors2024

A Multicomponent Intervention (POSSIBLE) to Improve Perceived Risk for HIV Among Black Sexual Minority Men: Feasibility and Preliminary Effectiveness Pilot Study.

Derek T Dangerfield Ii, Janeane N Anderson, Charleen Wylie, Ricky Bluthenthal, Chris Beyrer, Jason E Farley

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in JMIR human factors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04533386 (A Multicomponent Intervention to Increase HIV Risk Perceptions and PrEP Initiation Among Black Men Who Have Sex With Men), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04533386 nacompletednot on this map

A Multicomponent Intervention to Increase HIV Risk Perceptions and PrEP Initiation Among Black Men Who Have Sex With Men

TypeinterventionalSponsorGeorge Washington UniversityRan2020 to 2022Enrolled69ConditionsHIV Risk Perception, PrEPArmsMulti-component intervention strategy
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Derek T Dangerfield Ii *Milken Institute School of Public Health, George Washington University, Washington, DC, United States.ORCID 0000-0002-2473-3183
Janeane N AndersonUniversity of Tennessee Health Science Center, Memphis, TN, United States.ORCID 0000-0003-2602-6957
Charleen WylieMilken Institute School of Public Health, George Washington University, Washington, DC, United States.ORCID 0000-0003-3745-1238
Ricky BluthenthalKeck School of Medicine of USC, University of Southern California, Los Angeles, CA, United States.ORCID 0000-0003-3491-1702
Chris BeyrerDuke Global Health Institute, Durham, NC, United States.ORCID 0000-0003-0665-9124
Jason E FarleyJohns Hopkins School of Nursing, Baltimore, MD, United States.ORCID 0000-0002-6896-0134

Funding

Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Anna Palmer Durbin · 2012 to 2026
$67.0M
NEURAL BASIS OF RESPONSE SELECTIONF32MH011849 · NIMH · STANFORD UNIVERSITY · PI HAZELTINE, RICHARD ELIOT · 1998 to 1998
–
NIAID NIH HHS P30 AI094189NIMH NIH HHS F32 MH011849
6 · The paper itself

Abstract

backgroundIncreased pre-exposure prophylaxis (PrEP) use is urgently needed to substantially decrease HIV incidence among Black sexual minority men. Low perceived risk for HIV (PRH) is a key unaddressed PrEP barrier for Black sexual minority men. Peers and smartphone apps are popular intervention tools to promote community health behaviors, but few studies have used these together in a multicomponent strategy. Therefore, we designed a multicomponent intervention called POSSIBLE that used an existing smartphone app called PrEPme (Emocha Mobile Health, Inc) and a peer change agent (PCA) to increase PRH as a gateway to PrEP.

objectiveThis paper aims to describe the feasibility and preliminary impact of POSSIBLE on PRH and willingness to accept a PrEP referral among Black sexual minority men.

methodsPOSSIBLE was a theoretically guided, single-group, 2-session pilot study conducted among Black sexual minority men from Baltimore, Maryland between 2019 and 2021 (N=69). POSSIBLE integrated a PCA and the PrEPme app that allows users to self-monitor sexual risk behaviors and chat with the in-app community health worker to obtain PrEP service information. PRH was assessed using the 8-item PRH scale before and after baseline and follow-up study visits. At the end of each study visit, the PCA referred interested individuals to the community health worker to learn more about PrEP service options.

resultsThe average age of participants was 32.5 (SD 8.1, range 19-62) years. In total, 55 (80%) participants were retained for follow-up at month 1. After baseline sessions, 29 (42%) participants were willing to be referred to PrEP services, 20 (69%) of those confirmed scheduled appointments with PrEP care teams. There were no statistically significant differences in PRH between baseline and follow-up visits (t

conclusionsWe observed no statistically significant improvement in PRH between baseline and month 1. However, given the high retention rate and acceptability, POSSIBLE may be feasible to implement. Future research should test a statistically powered peer-based approach on PrEP initiation among Black sexual minority men.

trial registrationClinicalTrials.gov NCT04533386; https://clinicaltrials.gov/study/NCT04533386.

Indexed as

Black or African AmericanHIV InfectionsPre-Exposure ProphylaxisSexual and Gender MinoritiesAdultBaltimoreFeasibility StudiesHumansMaleMiddle AgedMobile ApplicationsPilot ProjectsYoung AdultAfrican AmericanappsBlackcommunitycommunity healthdigital healthdigital interventionsdigital technologyHIVminorityminority communitiesmobile healthmobile phonepatient educationpeerspre-exposure prophylaxisPrEPself-monitoringsexual healthsexual minoritysmartphonestreatment adherencetreatment participation

Identifiers

PMID38861707
PMCPMC11200034

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.