Evidence map›Paper›PMID 38861354›Full record

ArticleAmerican journal of respiratory cell and molecular biology2024

Collagen 18A1/Endostatin Expression in the Progression of Right Ventricular Remodeling and Dysfunction in Pulmonary Arterial Hypertension.

Anjira S Ambade, Mario Naranjo, Tijana Tuhy, Rose Yu, Mery Marimoutou, Allen D Everett, Larissa A Shimoda, Stefan L Zimmerman, Ilton M Cubero Salazar, Catherine E Simpson and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of respiratory cell and molecular biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. BMP9 regulates the endothelial secretome to drive pulmonary hypertension.bioRxiv : the preprint server for biology · 2025
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Anjira S AmbadeDivision of Pulmonary and Critical Care Medicine.
Mario NaranjoDepartment of Thoracic Medicine and Surgery, Temple University, Philadelphia, Pennsylvania.
Tijana TuhyDivision of Pulmonary and Critical Care Medicine.
Rose YuDivision of Pulmonary Medicine, Johns Hopkins Community Physicians, Columbia, Maryland.
Mery MarimoutouInstitute for In Vitro Sciences, Gaithersburg, Maryland; and.
Allen D EverettDivision of Pediatric Cardiology, Department of Pediatrics.
Larissa A ShimodaDivision of Pulmonary and Critical Care Medicine.
Stefan L ZimmermanDepartment of Radiology and Radiological Science, and.
Ilton M Cubero SalazarDivision of Cardiology, Department of Medicine.ORCID 0000-0002-1949-1749
Catherine E SimpsonDivision of Pulmonary and Critical Care Medicine.ORCID 0000-0002-2388-5660
Ryan J TedfordDivision of Cardiology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina.
Steven HsuDivision of Cardiology, Department of Medicine.
Paul M HassounDivision of Pulmonary and Critical Care Medicine.ORCID 0000-0003-0601-4975
Rachel L DamicoDivision of Pulmonary and Critical Care Medicine.ORCID 0000-0002-2584-1557

Funding

MULTIDISCIPLINARY TRAINING PROGRAM IN LUNG DISEASEST32HL007534 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Nadia N Hansel, Larissa A. Shimoda · 1985 to 2026
$28.3M
Mechanisms of Right Ventricular Dysfunction in Scleroderma-associated PAHR01HL114910 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI HASSOUN, PAUL M. · 2012 to 2023
$6.2M
Aquaporin 1 and pulmonary hypertensionR01HL126514 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI SHIMODA, LARISSA A. · 2015 to 2025
$4.5M
Clinical and mechanistic role of HDGF in pulmonary hypertensionR01HL135114 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI EVERETT, ALLEN D · 2017 to 2020
$2.9M
Functional Impact of Col18a1/Endostatin Variants in PAHR01HL132153 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI DAMICO, RACHEL L, HASSOUN, PAUL M. · 2017 to 2020
$2.5M
Myocyte Mechanics of Right Ventricular Contractile Failure in Pulmonary Hypertension due to Heart Failure with Reduced Ejection FractionR01HL172830 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Steven Hsu · 2024 to 2026
$2.0M
Mechanisms and treatment of right ventricular sarcomere dysfunction in scleroderma-associated pulmonary arterial hypertensionK23HL146889 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI HSU, STEVEN · 2019 to 2023
$886k
National Scleroderma FoundationNHLBI NIH HHS K23 HL146889NHLBI NIH HHS R01 HL114910NHLBI NIH HHS R01 HL126514NHLBI NIH HHS R01 HL132153NHLBI NIH HHS R01 HL135114NHLBI NIH HHS R01 HL172830NHLBI NIH HHS T32 HL007534NIH HHS HL007534-31A1Pulmonary Hypertension Association
6 · The paper itself

Abstract

Numerous studies have demonstrated that endostatin (ES), a potent angiostatic peptide derived from collagen type XVIII α 1 chain and encoded by

Indexed as

EndostatinsVentricular Dysfunction, RightVentricular RemodelingAdultAnimalsCollagen Type XVIIIDisease Models, AnimalDisease ProgressionFemaleHeart VentriclesHumansHypertension, PulmonaryMaleMiddle AgedPulmonary Arterial HypertensionRatsCollagen Type XVIIIEndostatinsendostatinpulmonary arterial hypertensionright heart

Identifiers

PMID38861354
PMCPMC11376241

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.