ReviewNatural products and bioprospecting2024
Recent advances in the application of [2 + 2] cycloaddition in the chemical synthesis of cyclobutane-containing natural products.
Review in Natural products and bioprospecting, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Substituent-controlled visible light photoisomerization and cyclodimerization of styryl pyrimidinones.RSC advances · 2026Article
- Diradical Character of Cyclic Allenes Enables Their Thermal (2 + 2) Cycloadditions.Journal of the American Chemical Society · 2026Article
- Reenvisioning the De Mayo Reaction: A Boron-Enabled Cycloaddition Approach.Angewandte Chemie (International ed. in English) · 2026Article
- Synthesis and Ring Expansion of Triflylated Cyclobutenyl MIDA Boronates.Organic letters · 2026Article
- Emerging enzymatic strategies for the synthesis of α-tertiary amino acids.Communications chemistry · 2026Review
- Ab Initio Molecular Dynamics Simulations for Organic Chemists─It is About Time!Journal of the American Chemical Society · 2026Review
- Harnessing Photochemistry in Natural Product Synthesis: From Strategy to Applications.Journal of natural products · 2025Review
- On the Question of the Regio-Orientation, Stereo-Orientation and Molecular Mechanism in the Cascade Cycloaddition/Rearrangement/Elimination Processes Leading to Nitro-Substituted Thiopyran Analogs: DFT Computational Study.International journal of molecular sciences · 2025Article
- Article
- Silvaticusins A-D: ent-kaurane diterpenoids and a cyclobutane-containing ent-kaurane dimer from Isodon silvaticus.Natural products and bioprospecting · 2024Article
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Authors and funding
4 authors.
Funding
Abstract
Cyclobutanes are distributed widely in a large class of natural products featuring diverse pharmaceutical activities and intricate structural frameworks. The [2 + 2] cycloaddition is unequivocally the primary and most commonly used method for synthesizing cyclobutanes. In this review, we have summarized the application of the [2 + 2] cycloaddition with different reaction mechanisms in the chemical synthesis of selected cyclobutane-containing natural products over the past decade.
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Registered trials
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