Evidence map›Paper›PMID 38861163›Full record

ArticleEuropean radiology2024

Bronchial artery embolization using small particles is safe and effective: a single center 12-year experience.

Frances Sheehan, Alison Graham, N Paul Tait, Philip Ind, Ali Alsafi, James E Jackson

Abstract read
In one paragraph

Article in European radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  11. Diagnosis and Embolization of Pulmonary Esophageal Artery Hemoptysis in Lower Lobe Pulmonary Disease: Single-Center Study.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Frances SheehanImaging Department, Imperial College Healthcare NHS Trust, London, UK.
Alison GrahamImaging Department, Imperial College Healthcare NHS Trust, London, UK.
N Paul TaitImaging Department, Imperial College Healthcare NHS Trust, London, UK.
Philip IndDepartment of Respiratory Medicine, Imperial College Healthcare NHS Trust, London, UK.
Ali AlsafiImaging Department, Imperial College Healthcare NHS Trust, London, UK. a.alsafi@imperial.ac.uk.ORCID http://orcid.org/0000-0001-6688-8637
James E JacksonImaging Department, Imperial College Healthcare NHS Trust, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBronchial artery embolization (BAE) using particles is an established treatment for hemoptysis. The use of polyvinyl alcohol (PVA) with a particle size of 300 µm or larger is thought to reduce the risk of non-target embolization but may result in more proximal vessel occlusion than is ideal, resulting in a high rate of early recurrent hemorrhage.

objectiveThis study evaluates the safety and efficacy of BAE using PVA particles with a size of less than 300 µm.

methodsAll patients who underwent BAE between 2010 and 2022 at a tertiary center were included. Demographic data, etiology and volume of hemoptysis, technical and clinical success, procedure-related complications, and follow-up information were collected from patients' electronic records. 150-250 µm PVA particles were used to commence embolization in all patients with the subsequent use of larger-sized particles in some individuals. The Kaplan-Meier method was used to estimate recurrence and survival rates.

resultsOne hundred forty-four patients underwent 189 embolization procedures between 2010 and 2022 and were followed up for a median of 35 months [IQR 19-89]. 150 µm to 250 µm PVA particles were used as the sole embolic agent in 137 cases. Hemoptysis recurred within 30 days in 7%. The median time to repeat intervention was 144 days [IQR 42-441]. Seventeen out of 144 patients had a pulmonary artery branch pseudoaneurysm. The rate of major complications was 1% with no instances of stroke or spinal artery ischemia. Thirty-day mortality was 2% (4/189).

conclusionBAE using 150-250 µm PVA particles is safe and effective with few complications and low rates of early hemoptysis recurrence. CLINICAL RELEVANCE STATEMENT: BAE using small particles is likely to improve outcomes, particularly the rate of early recurrence, in patients with hemoptysis, without an increase in procedural complications. KEY POINTS: BAE is a safe and effective treatment for patients with hemoptysis. Using small PVA particles in BAE has few complications and low rates of early recurrence. Pulmonary artery pseudoaneurysms should be actively sought in those with hemoptysis undergoing BAE.

Indexed as

Bronchial ArteriesEmbolization, TherapeuticHemoptysisParticle SizePolyvinyl AlcoholAdultAgedFemaleHumansMaleMiddle AgedRecurrenceRetrospective StudiesTreatment OutcomePolyvinyl AlcoholBronchial arteriesEmbolization (therapeutic)HemoptysisPolyvinyl alcohol

Identifiers

PMID38861163
PMCPMC11557673

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.