ArticleRadiology2024
AmyloidPETNet: Classification of Amyloid Positivity in Brain PET Imaging Using End-to-End Deep Learning.
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Article in Radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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17citing papers in PubMed, 1 pooled it
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Stage-stratified benefits of AI-radiomics PET in early Alzheimer's disease: a systematic review and meta-analysis.Frontiers in neurologyPooled it
- Brain PET in the era of anti-amyloid-β antibody therapy for Alzheimer disease.Japanese journal of radiology · 2026Review
- Stratifying amyloid burden in early Alzheimer's disease using cascaded attention-guided vision transformer using [¹⁸F]Florbetapir PET.European radiology · 2026Article
- SPECT and PET imaging of Alzheimer's disease revisited: from biomarkers to artificial intelligence-based prediction.Annals of nuclear medicine · 2026Review
- AI-enhanced Centiloid quantification of amyloid PET images.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Deep learning for FDG-PET classification in patients with Alzheimer's disease, dementia with Lewy bodies and their mixed pathology: a solution for diagnostic heterogeneity.Frontiers in aging neuroscience · 2026Article
- LNODE: Uncovering the Latent Dynamics ofMedical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2026Article
- Predicting future cognitive impairment in preclinical Alzheimer's disease using multimodal imaging: a multisite machine learning study.medRxiv : the preprint server for health sciences · 2025Article
- Anticlustering for sample allocation to minimize batch effects.Cell reports methods · 2025Article
- Protein-based Diagnosis and Analysis of Co-pathologies Across Neurodegenerative Diseases: Large-Scale AI-Boosted CSF and Plasma Classification.Research square · 2025Article
- Protein-based Diagnosis and Analysis of Co-pathologies Across Neurodegenerative Diseases: Large-Scale AI-Boosted CSF and Plasma Classification.medRxiv : the preprint server for health sciences · 2025Article
- Revisiting Centiloids using AI.Research square · 2025Article
- Deep Learning-Based Algorithm for Automatic Quantification of Nigrosome-1 and Parkinsonism Classification Using Susceptibility Map-Weighted MRI.AJNR. American journal of neuroradiology · 2025Article
- FLIM-Phasor Analysis (FLIM-ϕ) of Aβ-Induced Membrane Order Alterations: Towards a Cell-Based Biosensor for Early Alzheimer's Disease Diagnosis.Micromachines · 2025Article
- Interrater agreement and variability in visual reading of [18F] flutemetamol PET images.Annals of nuclear medicine · 2025Article
- Recent Advances in the Application of Artificial Intelligence in Alzheimer's Disease.Current Alzheimer research · 2025Review
- Artificial Intelligence in Radiology: Not If, But How and When.Radiology · 2024Article
Corrections and comments
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Authors and funding
18 authors.
Shuyang FanFrom the Department of Bioengineering, Rice University, Houston, Tex (S. Fan); Department of Radiology (S. Fan, M.R.P., P.X., S.M.H., J.J.L., S. Flores, P.L., B.G., C.A.R., D.S.M., A.N., T.L.S.B., A.S.), Charles F. and Joanne Knight Alzheimer Disease Research Center (B.G., B.M.A., R.B., J.C.M., T.L.S.B.), Department of Neurology (C.A.R., B.M.A., R.J.B., J.C.M.), and Institute for Informatics, Data Science and Biostatistics (A.S.), Washington University School of Medicine, 660 S Euclid Ave, Campus Box 8132, St Louis, MO 63110; Duke-NUS Medical School, Singapore (S. Fan); Department of Electrical and Systems Engineering, Washington University in St Louis, St Louis, Mo (S.C., A.S.); Brain Health Imaging Centre, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada (A.N.); and Tracy Family SILQ Center for Neurodegenerative Biology, St Louis, Mo (R.J.B.).ORCID 0000-0003-3171-1801
Maria Rosana PonisioFrom the Department of Bioengineering, Rice University, Houston, Tex (S. Fan); Department of Radiology (S. Fan, M.R.P., P.X., S.M.H., J.J.L., S. Flores, P.L., B.G., C.A.R., D.S.M., A.N., T.L.S.B., A.S.), Charles F. and Joanne Knight Alzheimer Disease Research Center (B.G., B.M.A., R.B., J.C.M., T.L.S.B.), Department of Neurology (C.A.R., B.M.A., R.J.B., J.C.M.), and Institute for Informatics, Data Science and Biostatistics (A.S.), Washington University School of Medicine, 660 S Euclid Ave, Campus Box 8132, St Louis, MO 63110; Duke-NUS Medical School, Singapore (S. Fan); Department of Electrical and Systems Engineering, Washington University in St Louis, St Louis, Mo (S.C., A.S.); Brain Health Imaging Centre, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada (A.N.); and Tracy Family SILQ Center for Neurodegenerative Biology, St Louis, Mo (R.J.B.).ORCID 0000-0002-4528-8971
Pan XiaoFrom the Department of Bioengineering, Rice University, Houston, Tex (S. Fan); Department of Radiology (S. Fan, M.R.P., P.X., S.M.H., J.J.L., S. Flores, P.L., B.G., C.A.R., D.S.M., A.N., T.L.S.B., A.S.), Charles F. and Joanne Knight Alzheimer Disease Research Center (B.G., B.M.A., R.B., J.C.M., T.L.S.B.), Department of Neurology (C.A.R., B.M.A., R.J.B., J.C.M.), and Institute for Informatics, Data Science and Biostatistics (A.S.), Washington University School of Medicine, 660 S Euclid Ave, Campus Box 8132, St Louis, MO 63110; Duke-NUS Medical School, Singapore (S. Fan); Department of Electrical and Systems Engineering, Washington University in St Louis, St Louis, Mo (S.C., A.S.); Brain Health Imaging Centre, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada (A.N.); and Tracy Family SILQ Center for Neurodegenerative Biology, St Louis, Mo (R.J.B.).ORCID 0009-0005-3319-0431
Sung Min HaFrom the Department of Bioengineering, Rice University, Houston, Tex (S. Fan); Department of Radiology (S. Fan, M.R.P., P.X., S.M.H., J.J.L., S. Flores, P.L., B.G., C.A.R., D.S.M., A.N., T.L.S.B., A.S.), Charles F. and Joanne Knight Alzheimer Disease Research Center (B.G., B.M.A., R.B., J.C.M., T.L.S.B.), Department of Neurology (C.A.R., B.M.A., R.J.B., J.C.M.), and Institute for Informatics, Data Science and Biostatistics (A.S.), Washington University School of Medicine, 660 S Euclid Ave, Campus Box 8132, St Louis, MO 63110; Duke-NUS Medical School, Singapore (S. Fan); Department of Electrical and Systems Engineering, Washington University in St Louis, St Louis, Mo (S.C., A.S.); Brain Health Imaging Centre, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada (A.N.); and Tracy Family SILQ Center for Neurodegenerative Biology, St Louis, Mo (R.J.B.).ORCID 0000-0002-3526-9101
Satrajit ChakrabartyFrom the Department of Bioengineering, Rice University, Houston, Tex (S. Fan); Department of Radiology (S. Fan, M.R.P., P.X., S.M.H., J.J.L., S. Flores, P.L., B.G., C.A.R., D.S.M., A.N., T.L.S.B., A.S.), Charles F. and Joanne Knight Alzheimer Disease Research Center (B.G., B.M.A., R.B., J.C.M., T.L.S.B.), Department of Neurology (C.A.R., B.M.A., R.J.B., J.C.M.), and Institute for Informatics, Data Science and Biostatistics (A.S.), Washington University School of Medicine, 660 S Euclid Ave, Campus Box 8132, St Louis, MO 63110; Duke-NUS Medical School, Singapore (S. Fan); Department of Electrical and Systems Engineering, Washington University in St Louis, St Louis, Mo (S.C., A.S.); Brain Health Imaging Centre, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada (A.N.); and Tracy Family SILQ Center for Neurodegenerative Biology, St Louis, Mo (R.J.B.).ORCID 0000-0002-9664-4470
John J LeeFrom the Department of Bioengineering, Rice University, Houston, Tex (S. Fan); Department of Radiology (S. Fan, M.R.P., P.X., S.M.H., J.J.L., S. Flores, P.L., B.G., C.A.R., D.S.M., A.N., T.L.S.B., A.S.), Charles F. and Joanne Knight Alzheimer Disease Research Center (B.G., B.M.A., R.B., J.C.M., T.L.S.B.), Department of Neurology (C.A.R., B.M.A., R.J.B., J.C.M.), and Institute for Informatics, Data Science and Biostatistics (A.S.), Washington University School of Medicine, 660 S Euclid Ave, Campus Box 8132, St Louis, MO 63110; Duke-NUS Medical School, Singapore (S. Fan); Department of Electrical and Systems Engineering, Washington University in St Louis, St Louis, Mo (S.C., A.S.); Brain Health Imaging Centre, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada (A.N.); and Tracy Family SILQ Center for Neurodegenerative Biology, St Louis, Mo (R.J.B.).
Shaney FloresFrom the Department of Bioengineering, Rice University, Houston, Tex (S. Fan); Department of Radiology (S. Fan, M.R.P., P.X., S.M.H., J.J.L., S. Flores, P.L., B.G., C.A.R., D.S.M., A.N., T.L.S.B., A.S.), Charles F. and Joanne Knight Alzheimer Disease Research Center (B.G., B.M.A., R.B., J.C.M., T.L.S.B.), Department of Neurology (C.A.R., B.M.A., R.J.B., J.C.M.), and Institute for Informatics, Data Science and Biostatistics (A.S.), Washington University School of Medicine, 660 S Euclid Ave, Campus Box 8132, St Louis, MO 63110; Duke-NUS Medical School, Singapore (S. Fan); Department of Electrical and Systems Engineering, Washington University in St Louis, St Louis, Mo (S.C., A.S.); Brain Health Imaging Centre, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada (A.N.); and Tracy Family SILQ Center for Neurodegenerative Biology, St Louis, Mo (R.J.B.).ORCID 0000-0003-2726-8704
Pamela LaMontagneFrom the Department of Bioengineering, Rice University, Houston, Tex (S. Fan); Department of Radiology (S. Fan, M.R.P., P.X., S.M.H., J.J.L., S. Flores, P.L., B.G., C.A.R., D.S.M., A.N., T.L.S.B., A.S.), Charles F. and Joanne Knight Alzheimer Disease Research Center (B.G., B.M.A., R.B., J.C.M., T.L.S.B.), Department of Neurology (C.A.R., B.M.A., R.J.B., J.C.M.), and Institute for Informatics, Data Science and Biostatistics (A.S.), Washington University School of Medicine, 660 S Euclid Ave, Campus Box 8132, St Louis, MO 63110; Duke-NUS Medical School, Singapore (S. Fan); Department of Electrical and Systems Engineering, Washington University in St Louis, St Louis, Mo (S.C., A.S.); Brain Health Imaging Centre, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada (A.N.); and Tracy Family SILQ Center for Neurodegenerative Biology, St Louis, Mo (R.J.B.).ORCID 0000-0002-6752-8518
Brian GordonFrom the Department of Bioengineering, Rice University, Houston, Tex (S. Fan); Department of Radiology (S. Fan, M.R.P., P.X., S.M.H., J.J.L., S. Flores, P.L., B.G., C.A.R., D.S.M., A.N., T.L.S.B., A.S.), Charles F. and Joanne Knight Alzheimer Disease Research Center (B.G., B.M.A., R.B., J.C.M., T.L.S.B.), Department of Neurology (C.A.R., B.M.A., R.J.B., J.C.M.), and Institute for Informatics, Data Science and Biostatistics (A.S.), Washington University School of Medicine, 660 S Euclid Ave, Campus Box 8132, St Louis, MO 63110; Duke-NUS Medical School, Singapore (S. Fan); Department of Electrical and Systems Engineering, Washington University in St Louis, St Louis, Mo (S.C., A.S.); Brain Health Imaging Centre, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada (A.N.); and Tracy Family SILQ Center for Neurodegenerative Biology, St Louis, Mo (R.J.B.).ORCID 0000-0003-2109-2955
Cyrus A RajiFrom the Department of Bioengineering, Rice University, Houston, Tex (S. Fan); Department of Radiology (S. Fan, M.R.P., P.X., S.M.H., J.J.L., S. Flores, P.L., B.G., C.A.R., D.S.M., A.N., T.L.S.B., A.S.), Charles F. and Joanne Knight Alzheimer Disease Research Center (B.G., B.M.A., R.B., J.C.M., T.L.S.B.), Department of Neurology (C.A.R., B.M.A., R.J.B., J.C.M.), and Institute for Informatics, Data Science and Biostatistics (A.S.), Washington University School of Medicine, 660 S Euclid Ave, Campus Box 8132, St Louis, MO 63110; Duke-NUS Medical School, Singapore (S. Fan); Department of Electrical and Systems Engineering, Washington University in St Louis, St Louis, Mo (S.C., A.S.); Brain Health Imaging Centre, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada (A.N.); and Tracy Family SILQ Center for Neurodegenerative Biology, St Louis, Mo (R.J.B.).
Daniel S MarcusFrom the Department of Bioengineering, Rice University, Houston, Tex (S. Fan); Department of Radiology (S. Fan, M.R.P., P.X., S.M.H., J.J.L., S. Flores, P.L., B.G., C.A.R., D.S.M., A.N., T.L.S.B., A.S.), Charles F. and Joanne Knight Alzheimer Disease Research Center (B.G., B.M.A., R.B., J.C.M., T.L.S.B.), Department of Neurology (C.A.R., B.M.A., R.J.B., J.C.M.), and Institute for Informatics, Data Science and Biostatistics (A.S.), Washington University School of Medicine, 660 S Euclid Ave, Campus Box 8132, St Louis, MO 63110; Duke-NUS Medical School, Singapore (S. Fan); Department of Electrical and Systems Engineering, Washington University in St Louis, St Louis, Mo (S.C., A.S.); Brain Health Imaging Centre, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada (A.N.); and Tracy Family SILQ Center for Neurodegenerative Biology, St Louis, Mo (R.J.B.).ORCID 0000-0001-5662-5358
Arash NazeriFrom the Department of Bioengineering, Rice University, Houston, Tex (S. Fan); Department of Radiology (S. Fan, M.R.P., P.X., S.M.H., J.J.L., S. Flores, P.L., B.G., C.A.R., D.S.M., A.N., T.L.S.B., A.S.), Charles F. and Joanne Knight Alzheimer Disease Research Center (B.G., B.M.A., R.B., J.C.M., T.L.S.B.), Department of Neurology (C.A.R., B.M.A., R.J.B., J.C.M.), and Institute for Informatics, Data Science and Biostatistics (A.S.), Washington University School of Medicine, 660 S Euclid Ave, Campus Box 8132, St Louis, MO 63110; Duke-NUS Medical School, Singapore (S. Fan); Department of Electrical and Systems Engineering, Washington University in St Louis, St Louis, Mo (S.C., A.S.); Brain Health Imaging Centre, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada (A.N.); and Tracy Family SILQ Center for Neurodegenerative Biology, St Louis, Mo (R.J.B.).ORCID 0000-0001-6983-0641
Beau M AncesFrom the Department of Bioengineering, Rice University, Houston, Tex (S. Fan); Department of Radiology (S. Fan, M.R.P., P.X., S.M.H., J.J.L., S. Flores, P.L., B.G., C.A.R., D.S.M., A.N., T.L.S.B., A.S.), Charles F. and Joanne Knight Alzheimer Disease Research Center (B.G., B.M.A., R.B., J.C.M., T.L.S.B.), Department of Neurology (C.A.R., B.M.A., R.J.B., J.C.M.), and Institute for Informatics, Data Science and Biostatistics (A.S.), Washington University School of Medicine, 660 S Euclid Ave, Campus Box 8132, St Louis, MO 63110; Duke-NUS Medical School, Singapore (S. Fan); Department of Electrical and Systems Engineering, Washington University in St Louis, St Louis, Mo (S.C., A.S.); Brain Health Imaging Centre, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada (A.N.); and Tracy Family SILQ Center for Neurodegenerative Biology, St Louis, Mo (R.J.B.).
Randall J BatemanFrom the Department of Bioengineering, Rice University, Houston, Tex (S. Fan); Department of Radiology (S. Fan, M.R.P., P.X., S.M.H., J.J.L., S. Flores, P.L., B.G., C.A.R., D.S.M., A.N., T.L.S.B., A.S.), Charles F. and Joanne Knight Alzheimer Disease Research Center (B.G., B.M.A., R.B., J.C.M., T.L.S.B.), Department of Neurology (C.A.R., B.M.A., R.J.B., J.C.M.), and Institute for Informatics, Data Science and Biostatistics (A.S.), Washington University School of Medicine, 660 S Euclid Ave, Campus Box 8132, St Louis, MO 63110; Duke-NUS Medical School, Singapore (S. Fan); Department of Electrical and Systems Engineering, Washington University in St Louis, St Louis, Mo (S.C., A.S.); Brain Health Imaging Centre, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada (A.N.); and Tracy Family SILQ Center for Neurodegenerative Biology, St Louis, Mo (R.J.B.).
John C MorrisFrom the Department of Bioengineering, Rice University, Houston, Tex (S. Fan); Department of Radiology (S. Fan, M.R.P., P.X., S.M.H., J.J.L., S. Flores, P.L., B.G., C.A.R., D.S.M., A.N., T.L.S.B., A.S.), Charles F. and Joanne Knight Alzheimer Disease Research Center (B.G., B.M.A., R.B., J.C.M., T.L.S.B.), Department of Neurology (C.A.R., B.M.A., R.J.B., J.C.M.), and Institute for Informatics, Data Science and Biostatistics (A.S.), Washington University School of Medicine, 660 S Euclid Ave, Campus Box 8132, St Louis, MO 63110; Duke-NUS Medical School, Singapore (S. Fan); Department of Electrical and Systems Engineering, Washington University in St Louis, St Louis, Mo (S.C., A.S.); Brain Health Imaging Centre, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada (A.N.); and Tracy Family SILQ Center for Neurodegenerative Biology, St Louis, Mo (R.J.B.).ORCID 0000-0001-9820-5618
Tammie L S BenzingerFrom the Department of Bioengineering, Rice University, Houston, Tex (S. Fan); Department of Radiology (S. Fan, M.R.P., P.X., S.M.H., J.J.L., S. Flores, P.L., B.G., C.A.R., D.S.M., A.N., T.L.S.B., A.S.), Charles F. and Joanne Knight Alzheimer Disease Research Center (B.G., B.M.A., R.B., J.C.M., T.L.S.B.), Department of Neurology (C.A.R., B.M.A., R.J.B., J.C.M.), and Institute for Informatics, Data Science and Biostatistics (A.S.), Washington University School of Medicine, 660 S Euclid Ave, Campus Box 8132, St Louis, MO 63110; Duke-NUS Medical School, Singapore (S. Fan); Department of Electrical and Systems Engineering, Washington University in St Louis, St Louis, Mo (S.C., A.S.); Brain Health Imaging Centre, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada (A.N.); and Tracy Family SILQ Center for Neurodegenerative Biology, St Louis, Mo (R.J.B.).ORCID 0000-0002-8114-0552
Aristeidis SotirasFrom the Department of Bioengineering, Rice University, Houston, Tex (S. Fan); Department of Radiology (S. Fan, M.R.P., P.X., S.M.H., J.J.L., S. Flores, P.L., B.G., C.A.R., D.S.M., A.N., T.L.S.B., A.S.), Charles F. and Joanne Knight Alzheimer Disease Research Center (B.G., B.M.A., R.B., J.C.M., T.L.S.B.), Department of Neurology (C.A.R., B.M.A., R.J.B., J.C.M.), and Institute for Informatics, Data Science and Biostatistics (A.S.), Washington University School of Medicine, 660 S Euclid Ave, Campus Box 8132, St Louis, MO 63110; Duke-NUS Medical School, Singapore (S. Fan); Department of Electrical and Systems Engineering, Washington University in St Louis, St Louis, Mo (S.C., A.S.); Brain Health Imaging Centre, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada (A.N.); and Tracy Family SILQ Center for Neurodegenerative Biology, St Louis, Mo (R.J.B.).ORCID 0000-0003-0795-8820
Alzheimer's Disease Neuroimaging Initiative *From the Department of Bioengineering, Rice University, Houston, Tex (S. Fan); Department of Radiology (S. Fan, M.R.P., P.X., S.M.H., J.J.L., S. Flores, P.L., B.G., C.A.R., D.S.M., A.N., T.L.S.B., A.S.), Charles F. and Joanne Knight Alzheimer Disease Research Center (B.G., B.M.A., R.B., J.C.M., T.L.S.B.), Department of Neurology (C.A.R., B.M.A., R.J.B., J.C.M.), and Institute for Informatics, Data Science and Biostatistics (A.S.), Washington University School of Medicine, 660 S Euclid Ave, Campus Box 8132, St Louis, MO 63110; Duke-NUS Medical School, Singapore (S. Fan); Department of Electrical and Systems Engineering, Washington University in St Louis, St Louis, Mo (S.C., A.S.); Brain Health Imaging Centre, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada (A.N.); and Tracy Family SILQ Center for Neurodegenerative Biology, St Louis, Mo (R.J.B.).
Funding
Smartphone-Based "Burst" Cognitive AssessmentsP01AG003991 · NIA · WASHINGTON UNIVERSITY · PI JOHN MORRIS · 1985 to 2026
$69.5MThe natural history of AB accumulation in preclinical ADP01AG026276 · NIA · WASHINGTON UNIVERSITY · PI MORRIS, JOHN · 2005 to 2025
$49.5MBlood amyloid, tau, and neurodegeneration biomarkers and prediction of clinical onset, cognitive decline, and dementia diagnosisR01AG061900 · NIA · WASHINGTON UNIVERSITY · PI RANDALL J BATEMAN · 2024 to 2026
$16.8MBlood amyloid-beta relationship with amyloid plaques and CSF amyloid-betaRF1AG061900 · NIA · WASHINGTON UNIVERSITY · PI BATEMAN, RANDALL J · 2019 to 2020
$6.9MAdvanced machine learning algorithms that integrate multi-modal neuroimaging to quantify the heterogeneity in Alzheimer's DiseaseR01AG067103 · NIA · WASHINGTON UNIVERSITY · PI SOTIRAS, ARISTEIDIS · 2021 to 2025
$2.8MHIGH PERFORMANCE BIOMEDICAL IMAGING COMPUTER RESOURCESS10RR022984 · NCRR · WASHINGTON UNIVERSITY · PI PRIOR, FRED WILLIAM · 2009 to 2009
$1.9MA High Performance Research Image Repository (RIR) for the Washington University Center of High Performance Computing (CHPC)S10OD030477 · OD · WASHINGTON UNIVERSITY · PI MARCUS, DANIEL SCOTT · 2021 to 2021
$1.9MGPU COMPUTING RESOURCE TO ENABLE INNOVATION IN IMAGING AND NETWORK BIOLOGYS10OD018091 · OD · WASHINGTON UNIVERSITY · PI PAPPU, ROHIT V, PRIOR, FRED WILLIAM · 2014 to 2014
$598kAcquisition of a next-generation computing clusterS10OD025200 · OD · WASHINGTON UNIVERSITY · PI TOBIAS, MALCOLM · 2019 to 2019
$597kNCRR NIH HHS S10 RR022984NIA NIH HHS P01 AG003991NIA NIH HHS P01 AG026276NIA NIH HHS R01 AG061900NIA NIH HHS R01 AG067103NIA NIH HHS RF1 AG061900NIH HHS S10 OD018091NIH HHS S10 OD025200NIH HHS S10 OD030477
Abstract
Background Visual assessment of amyloid PET scans relies on the availability of radiologist expertise, whereas quantification of amyloid burden typically involves MRI for processing and analysis, which can be computationally expensive. Purpose To develop a deep learning model to classify minimally processed brain PET scans as amyloid positive or negative, evaluate its performance on independent data sets and different tracers, and compare it with human visual reads. Materials and Methods This retrospective study used 8476 PET scans (6722 patients) obtained from late 2004 to early 2023 that were analyzed across five different data sets. A deep learning model, AmyloidPETNet, was trained on 1538 scans from 766 patients, validated on 205 scans from 95 patients, and internally tested on 184 scans from 95 patients in the Alzheimer's Disease Neuroimaging Initiative (ADNI) fluorine 18 (
Indexed as
Alzheimer DiseaseBrainDeep LearningPositron-Emission TomographyAgedAged, 80 and overAmyloidFemaleHumansMaleRetrospective StudiesAmyloid
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