Evidence map›Paper›PMID 38860521›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2024

Cumulus: a federated electronic health record-based learning system powered by Fast Healthcare Interoperability Resources and artificial intelligence.

Andrew J McMurry, Daniel I Gottlieb, Timothy A Miller, James R Jones, Ashish Atreja, Jennifer Crago, Pankaja M Desai, Brian E Dixon, Matthew Garber, Vladimir Ignatov and 9 more

Abstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Observational
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Towards cross-application model-agnostic federated cohort discovery.Journal of the American Medical Informatics Association : JAMIA · 2024
    Article
  11. Standards and frameworks.Journal of the American Medical Informatics Association : JAMIA · 2024
    Article
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Andrew J McMurryComputational Health Informatics Program, Boston Children's Hospital, Boston, MA 02215, United States.
Daniel I GottliebComputational Health Informatics Program, Boston Children's Hospital, Boston, MA 02215, United States.
Timothy A MillerComputational Health Informatics Program, Boston Children's Hospital, Boston, MA 02215, United States.ORCID 0000-0003-4513-403X
James R JonesComputational Health Informatics Program, Boston Children's Hospital, Boston, MA 02215, United States.
Ashish AtrejaInnovation Technology, UC Davis Health, Rancho Cordova, CA 95670, United States.
Jennifer CragoCenter for Biomedical Informatics, Regenstrief Institute, Indianapolis, IN 46202, United States.
Pankaja M DesaiDepartment of Internal Medicine, Rush University Medical Center, Chicago, IL 60612, United States.ORCID 0000-0002-0904-5905
Brian E DixonCenter for Biomedical Informatics, Regenstrief Institute, Indianapolis, IN 46202, United States.ORCID 0000-0002-1121-0607
Matthew GarberComputational Health Informatics Program, Boston Children's Hospital, Boston, MA 02215, United States.
Vladimir IgnatovComputational Health Informatics Program, Boston Children's Hospital, Boston, MA 02215, United States.
Lyndsey A KirchnerCDC Foundation, Atlanta, GA 30308, United States.
Philip R O PayneInstitute for Informatics, Data Science, and Biostatistics, Washington University School of Medicine in St Louis, St Louis, MO 63110, United States.ORCID 0000-0002-9532-2998
Anil J SaldanhaDepartment of Health Innovation, Rush University Medical Center, Chicago, IL 60612, United States.
Prabhu R V ShankarInnovation Technology, UC Davis Health, Rancho Cordova, CA 95670, United States.
Yauheni V SoladInnovation Technology, UC Davis Health, Rancho Cordova, CA 95670, United States.
Elizabeth A SprouseDouble Lantern Informatics, Atlanta, GA 30305, United States.
Michael TerryComputational Health Informatics Program, Boston Children's Hospital, Boston, MA 02215, United States.
Adam B WilcoxInstitute for Informatics, Data Science, and Biostatistics, Washington University School of Medicine in St Louis, St Louis, MO 63110, United States.
Kenneth D MandlComputational Health Informatics Program, Boston Children's Hospital, Boston, MA 02215, United States.ORCID 0000-0002-9781-0477

Funding

Instrumenting the Delivery System for a Genomics Research Information CommonsU01TR002623 · NCATS · BOSTON CHILDREN'S HOSPITAL · PI MANDL, KENNETH D. · 2019 to 2024
$8.6M
Translating Scientific Evidence into Practice using Digital Medicine and Electronic Patient Reported OutcomesU01TR002997 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ATREJA, ASHISH, RIZK, MAGED · 2020 to 2023
$4.7M
ACL HHS U18DP006500CDC HHSCDC HHS NU38OT000286CDC HHS NU58IP000004CDC HHS U18DP006500Centers for Disease Control and Prevention Cooperative NU58IP000004National Association of Chronic Disease DirectorsNational Coordinator for Health Information Technology 90AX0031/01-00National Institutes of Health Cooperative U01TR002623NCATS NIH HHS U01 TR002623NCATS NIH HHS U01 TR002997NCCDPHP CDC HHS U18 DP006500NIH HHS U01TR002623ONCHIT HHS 90AX0031/01-00OSTLTS CDC HHS NU38OT000286United States Department of Health and Human Services
6 · The paper itself

Abstract

objectiveTo address challenges in large-scale electronic health record (EHR) data exchange, we sought to develop, deploy, and test an open source, cloud-hosted app "listener" that accesses standardized data across the SMART/HL7 Bulk FHIR Access application programming interface (API).

methodsWe advance a model for scalable, federated, data sharing and learning. Cumulus software is designed to address key technology and policy desiderata including local utility, control, and administrative simplicity as well as privacy preservation during robust data sharing, and artificial intelligence (AI) for processing unstructured text.

resultsCumulus relies on containerized, cloud-hosted software, installed within a healthcare organization's security envelope. Cumulus accesses EHR data via the Bulk FHIR interface and streamlines automated processing and sharing. The modular design enables use of the latest AI and natural language processing tools and supports provider autonomy and administrative simplicity. In an initial test, Cumulus was deployed across 5 healthcare systems each partnered with public health. Cumulus output is patient counts which were aggregated into a table stratifying variables of interest to enable population health studies. All code is available open source. A policy stipulating that only aggregate data leave the institution greatly facilitated data sharing agreements. DISCUSSION AND

conclusionCumulus addresses barriers to data sharing based on (1) federally required support for standard APIs, (2) increasing use of cloud computing, and (3) advances in AI. There is potential for scalability to support learning across myriad network configurations and use cases.

Indexed as

Artificial IntelligenceElectronic Health RecordsCloud ComputingHealth Information InteroperabilityHumansInformation DisseminationSoftwareelectronic health recordfederated networksinteroperabilitypublic health

Identifiers

PMID38860521
PMCPMC11258401

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.