Evidence map›Paper›PMID 38860337›Full record

ArticleTechnology in cancer research & treatment

Comparison of the Ability of Gadobenate Dimeglumine and Gadolinium Ethoxybenzyl Dimeglumine to Display the major Features for Noninvasively Diagnosing Hepatocellular Carcinoma According to the LI-RADS 2018v.

Wei-Wei Yao, Han-Wen Zhang, Yu-Pei M, Jia-Min Lee, Rui-Ting Lee, Yu-Li Wang, Xiao-Lei Liu, Xin-Ping Shen, Biao Huang, Fan Lin

Abstract readComparative Study
In one paragraph

Article in Technology in cancer research & treatment. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wei-Wei YaoDepartment of Radiology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China.
Han-Wen ZhangDepartment of Radiology, the First Affiliated Hospital of Shenzhen University, Health Science Center, Shenzhen Second People's Hospital, Shenzhen, China.ORCID 0000-0001-5731-7429
Yu-Pei MDepartment of Radiology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China.
Jia-Min LeeDepartment of Pathology, The University of Hong Kong -Shenzhen Hospital, Shenzhen, China.
Rui-Ting LeeDepartment of Radiology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China.
Yu-Li WangDepartment of Radiology, the First Affiliated Hospital of Shenzhen University, Health Science Center, Shenzhen Second People's Hospital, Shenzhen, China.
Xiao-Lei LiuDepartment of Radiology, the First Affiliated Hospital of Shenzhen University, Health Science Center, Shenzhen Second People's Hospital, Shenzhen, China.
Xin-Ping ShenDepartment of Radiology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China.
Biao HuangDepartment of Radiology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.
Fan LinDepartment of Radiology, the First Affiliated Hospital of Shenzhen University, Health Science Center, Shenzhen Second People's Hospital, Shenzhen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the ability of gadolinium ethoxybenzyl dimeglumine (Gd-EOB-DTPA) and gadobenate dimeglumine (Gd-BOPTA) to display the 3 major features recommended by the Liver Imaging Reporting and Data System (LI-RADS 2018v) for diagnosing hepatocellular carcinoma (HCC). MATERIALS AND

methodsIn this retrospective study, we included 98 HCC lesions that were scanned with either Gd-EOB-DTPA-MR or Gd-BOPTA-M.For each lesion, we collected multiple variables, including size and enhancement pattern in the arterial phase (AP), portal venous phase (PVP), transitional phase (TP), delayed phase (DP), and hepatobiliary phase (HBP). The lesion-to-liver contrast (LLC) was measured and calculated for each phase and then compared between the 2 contrast agents. A

resultsBetween Gd-BOPTA and Gd-EOB-DTPA, significant differences were observed regarding the display efficiency for capsule enhancement and the LLC in the AP/PVP/DP (

conclusionGd-BOPTA and Gd-EOB-DTPA are liver-specific contrast agents widely used in clinical practice. They have their own characteristics in displaying the 3 main signs of HCC. For accurate noninvasive diagnosis, the choice of agent should be made according to the specific situation.

Indexed as

Carcinoma, HepatocellularContrast MediaGadolinium DTPALiver NeoplasmsMagnetic Resonance ImagingMeglumineOrganometallic CompoundsROC CurveAdultAgedAged, 80 and overFemaleHumansImage EnhancementMaleMiddle AgedContrast Mediagadobenic acidGadolinium DTPAgadolinium ethoxybenzyl DTPAMeglumineOrganometallic CompoundsGd-BOPTAGd-EOB-DTPAhepatocellular carcinomaLI-RADS 2018v

Identifiers

PMID38860337
PMCPMC11168249

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.