Evidence map›Paper›PMID 38860230›Full record

ReviewBMJ neurology open2024

Reflections on the CODES trial for adults with dissociative seizures: what we found and considerations for future studies.

Laura H Goldstein, Jon Stone, Markus Reuber, Sabine Landau, Emily J Robinson, Alan Carson, Nick Medford, Trudie Chalder

Abstract readReview
In one paragraph

Review in BMJ neurology open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Laura H GoldsteinDepartment of Psychology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.ORCID 0000-0001-9387-3035
Jon StoneDepartment of Clinical Neuroscience, Centre for Clinical Brain Sciences, The University of Edinburgh, Edinburgh, UK.ORCID 0000-0001-9829-8092
Markus ReuberAcademic Neurology Unit, Royal Hallamshire Hospital, The University of Sheffield, Sheffield, UK.ORCID 0000-0002-4104-6705
Sabine LandauDepartment of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.ORCID 0000-0002-3615-8075
Emily J RobinsonSchool of Population Health and Environmental Sciences, King's College London, London, UK.ORCID 0000-0002-6692-5415
Alan CarsonDepartment of Clinical Neuroscience, Centre for Clinical Brain Sciences, The University of Edinburgh, Edinburgh, UK.ORCID 0000-0002-7425-0964
Nick MedfordSouth London and Maudsley NHS Foundation Trust, London, UK.ORCID 0000-0001-6739-6001
Trudie ChalderDepartment of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.ORCID 0000-0003-0775-1045

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COgnitive behavioural therapy versus standardised medical care for adults with Dissociative non-Epileptic Seizures multicentre randomised controlled trial is the largest, fully-powered study to test the clinical and cost-effectiveness of a psychotherapeutic intervention in this population. We also explored predictors or moderators of outcomes and investigated mechanisms of change in therapy. In this current review of findings, we discuss issues related to the design of the trial and consider the study's nested qualitative studies which were undertaken not only to shed light on the original research questions but to provide insights and recommendations for other researchers in the field of functional neurological disorder. Finally, we consider issues relating to the possible clinical application of our study findings.

Indexed as

RANDOMISED TRIALS

Identifiers

PMID38860230
PMCPMC11163627

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.