Evidence map›Paper›PMID 38860204›Full record

ArticleFrontiers in medicine2024

Transforming evidence-based clinical guidelines into implementable clinical decision support services: the CAREPATH study for multimorbidity management.

Mert Gencturk, Gokce B Laleci Erturkmen, A Emre Akpinar, Omid Pournik, Bilal Ahmad, Theodoros N Arvanitis, Wolfgang Schmidt-Barzynski, Tim Robbins, Ruben Alcantud Corcoles, Pedro Abizanda

Abstract read
In one paragraph

Article in Frontiers in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mert Gencturk *SRDC Software Research & Development and Consultancy Corporation, Ankara, Türkiye.
Gokce B Laleci Erturkmen *SRDC Software Research & Development and Consultancy Corporation, Ankara, Türkiye.
A Emre AkpinarSRDC Software Research & Development and Consultancy Corporation, Ankara, Türkiye.
Omid PournikDepartment of Electronic, Electrical and Systems Engineering, School of Engineering, University of Birmingham, Birmingham, United Kingdom.
Bilal AhmadDepartment of Electronic, Electrical and Systems Engineering, School of Engineering, University of Birmingham, Birmingham, United Kingdom.
Theodoros N ArvanitisDepartment of Electronic, Electrical and Systems Engineering, School of Engineering, University of Birmingham, Birmingham, United Kingdom.
Wolfgang Schmidt-BarzynskiUniversity Hospital OWL, Bielefeld, Germany.
Tim RobbinsDigital & Data Driven Research Unit, University Hospitals Coventry & Warwickshire NHS Trust, Coventry, United Kingdom.
Ruben Alcantud CorcolesGeriatrics Department, Complejo Hospitalario Universitario de Albacete, Albacete, Spain.
Pedro AbizandaGeriatrics Department, Complejo Hospitalario Universitario de Albacete, Albacete, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The CAREPATH Project aims to develop a patient-centered integrated care platform tailored to older adults with multimorbidity, including mild cognitive impairment (MCI) or mild dementia. Our goal is to empower multidisciplinary care teams to craft personalized holistic care plans while adhering to evidence-based guidelines. This necessitates the creation of clear specifications for clinical decision support (CDS) services, consolidating guidance from multiple evidence-based clinical guidelines. Thus, a co-creation approach involving both clinical and technical experts is essential. Methods: This paper outlines a robust methodology for generating implementable specifications for CDS services to automate clinical guidelines. We have established a co-creation framework to facilitate collaborative exploration of clinical guidelines between clinical experts and software engineers. We have proposed an open, repeatable, and traceable method for translating evidence-based guideline narratives into implementable specifications of CDS services. Our approach, based on international standards such as CDS-Hooks and HL7 FHIR, enhances interoperability and potential adoption of CDS services across diverse healthcare systems. Results: This methodology has been followed to create implementable specifications for 65 CDS services, automating CAREPATH consensus guideline consolidating guidance from 25 selected evidence-based guidelines. A total of 296 CDS rules have been formally defined, with input parameters defined as clinical concepts bound to FHIR resources and international code systems. Outputs include 346 well-defined CDS Cards, offering clear guidance for care plan activities and goal suggestions. These specifications have led to the implementation of 65 CDS services integrated into the CAREPATH Adaptive Integrated Care Platform. Discussion: Our methodology offers a systematic, replicable process for generating CDS specifications, ensuring consistency and reliability across implementation. By fostering collaboration between clinical expertise and technical proficiency, we enhance the quality and relevance of generated specifications. Clear traceability enables stakeholders to track the development process and ensure adherence to guideline recommendations.

Indexed as

automationclinical decision supportclinical guidelinedementiaHL7 FHIRintegrated caremultimorbidity

Identifiers

PMID38860204
PMCPMC11163046

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.