Evidence map›Paper›PMID 38859960›Full record

ArticleNeurology perspectives

Approach to non-compressive myeloneuropathy through a rendezvous of 11 cases from an Indian backdrop.

R Ghosh, D Roy, A Mandal, M León-Ruiz, S Das, S Dubey, A Jana, S Purkait, T Ghosh, J Benito-León

Abstract read
In one paragraph

Article in Neurology perspectives. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

R GhoshDepartment of General Medicine, Burdwan Medical College and Hospital, Burdwan, West Bengal, India.
D RoyDepartment of Biochemistry, All India Institute of Medical Sciences (AIIMS), Patna, Bihar, India.
A MandalDepartment of General Medicine, Burdwan Medical College and Hospital, Burdwan, West Bengal, India.
M León-RuizSection of Clinical Neurophysiology, Department of Neurology, University Hospital "La Paz", Madrid, Spain.
S DasDepartment of Neuromedicine, Bangur Institute of Neurosciences (BIN), Kolkata, West Bengal, India.
S DubeyDepartment of Neuromedicine, Bangur Institute of Neurosciences (BIN), Kolkata, West Bengal, India.
A JanaDepartment of Radio-diagnosis, Burdwan Medical College, and Hospital, Burdwan, West Bengal, India.
S PurkaitDepartment of General Medicine, Burdwan Medical College and Hospital, Burdwan, West Bengal, India.
T GhoshDepartment of Anatomy, Burdwan Medical College and Hospital, Burdwan, West Bengal, India.
J Benito-LeónDepartment of Neurology, University Hospital "12 de Octubre", Madrid, Spain.

Funding

ENVIRONMENTAL EPIDEMIOLOGY OF ESSENTIAL TREMORR01NS039422 · NINDS · YALE UNIVERSITY · PI LOUIS, ELAN D · 2000 to 2013
$7.7M
NINDS NIH HHS R01 NS039422
6 · The paper itself

Abstract

Introduction: Myeloneuropathy is a diagnosis ascribed to disorders that concomitantly affect the spinal cord and peripheral nerves. Recognizing this syndrome may sometimes be arduous, even for the most consummate clinicians, because symptomatology can mimic either spinal cord or peripheral nerve disease. Besides, examination findings suggest a predominantly myelopathic or neuropathic picture. This article reports a rendezvous of rare cases of clinically diagnosed myeloneuropathy with different etiological backgrounds and therapeutic responses. Methods: Eleven cases of non-compressive myeloneuropathy were admitted to the Department of General Medicine of Burdwan Medical College and Hospital, Burdwan, West Bengal, India, between May 2018 and May 2022. Results: We report the cases of 11 patients (6 men and 5 women) who presented with myeloneuropathy of different etiologies (vitamin B12, copper, and vitamin E deficiencies, organophosphate poisoning, chronic alcohol abuse, illicit substances abuse, anti-thyroid peroxidase/anti-thyroglobulin antibody-related neurologic disorder responsive to steroids, Sjögren syndrome, chikungunya infection, paraneoplastic, and hereditary). Conclusion: Meticulous historical analysis, careful clinical examination, and apposite utilization and interpretation of biochemical, electrophysiological, and neuroimaging findings are sine-qua-non for an accurate and consistent approach to evaluating a suspected case of myeloneuropathy, facilitating early treatment and recovery. Differential identification of these disorders needs an in-depth perception of the mode of onset of symptoms, the course of progression of the disease, the pattern of myelopathic/neuropathic findings, and recognition of other neurological or systemic manifestations. For untroubled understanding, etiologies of myeloneuropathies should be subdivided into a few broad categories, e.g., metabolic (nutritional), toxic (toxin-induced), infectious, inflammatory (immune-mediated), paraneoplastic, and hereditary disorders.

Indexed as

Case seriesDiagnostic ApproachesMyeloneuropathy

Identifiers

PMID38859960
PMCPMC11164299

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.