Evidence map›Paper›PMID 38859956›Full record

ReviewInternational journal of nanomedicine2024

Recent Updates of the CRISPR/Cas9 Genome Editing System: Novel Approaches to Regulate Its Spatiotemporal Control by Genetic and Physicochemical Strategies.

Khaled S Allemailem, Ahmad Almatroudi, Arshad Husain Rahmani, Faris Alrumaihi, Arwa Essa Alradhi, Amal M Alsubaiyel, Mohammad Algahtani, Rand Mohammad Almousa, Ali Mahzari, Abdulmajeed A A Sindi and 2 more

Abstract readReview
In one paragraph

Review in International journal of nanomedicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Khaled S AllemailemDepartment of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah 51452, Saudi Arabia.ORCID 0000-0002-6486-9835
Ahmad AlmatroudiDepartment of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah 51452, Saudi Arabia.ORCID 0000-0002-1491-6402
Arshad Husain RahmaniDepartment of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah 51452, Saudi Arabia.
Faris AlrumaihiDepartment of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah 51452, Saudi Arabia.ORCID 0000-0002-0850-5500
Arwa Essa AlradhiGeneral Administration for Infectious Disease Control, Ministry of Health, Riyadh 12382, Saudi Arabia.
Amal M AlsubaiyelDepartment of Pharmaceutics, College of Pharmacy, Qassim University, Buraydah 51452, Saudi Arabia.
Mohammad AlgahtaniDepartment of Laboratory & Blood Bank, Security Forces Hospital, Mecca 21955, Saudi Arabia.
Rand Mohammad AlmousaDepartment of Education, General Directorate of Education, Qassim 52361, Saudi Arabia.
Ali MahzariDepartment of Laboratory Medicine, Faculty of Applied Medical Sciences, Al-Baha University, Al-Baha 65527, Saudi Arabia.ORCID 0000-0002-6661-2320
Abdulmajeed A A SindiDepartment of Basic Medical Sciences, Faculty of Applied Medical Sciences, Al-Baha University, Al-Baha 65527, Saudi Arabia.
Gasim DobieDepartment of Medical Laboratory Technology, Faculty of Applied Medical Sciences, Jazan University, Gizan 82911, Saudi Arabia.ORCID 0000-0002-9225-1709
Amjad Ali KhanDepartment of Basic Health Sciences, College of Applied Medical Sciences, Qassim University, Buraydah 51452, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The genome editing approach by clustered regularly interspaced short palindromic repeats (CRISPR)/associated protein 9 (CRISPR/Cas9) is a revolutionary advancement in genetic engineering. Owing to its simple design and powerful genome-editing capability, it offers a promising strategy for the treatment of different infectious, metabolic, and genetic diseases. The crystal structure of

Indexed as

CRISPR-Cas SystemsGene EditingAnimalsCRISPR-Associated Protein 9HumansStreptococcus pyogenesCRISPR-Associated Protein 9clinical translationCRISPR/Cas9genome editingoff-target effectssgRNAspatiotemporal control

Identifiers

PMID38859956
PMCPMC11164216

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.