Evidence map›Paper›PMID 38859935›Full record

SynthesisFrontiers in genetics2024

What is the role of circRNAs in the pathogenesis of cervical cancer? A systematic literature review.

Ana Gabrielly de Melo Matos, Gyl Eanes Barros Silva, Eldevan da Silva Barbosa, Marcelo Souza de Andrade, Joyce Santos Lages, Rita da Graça Carvalhal Frazão Corrêa, Ana Gabriela Caldas Oliveira, Eliel Barbosa Teixeira, Marcelli Geisse de Oliveira Prata da Silva, Susanne Suely Santos da Fonseca and 5 more

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Frontiers in genetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Ana Gabrielly de Melo MatosPostgraduate Program in Adult Health, Federal University of Maranhão, São Luís, Brazil.
Gyl Eanes Barros SilvaPostgraduate Program in Adult Health, Federal University of Maranhão, São Luís, Brazil.
Eldevan da Silva BarbosaState University of Maranhão, Zé Doca, Maranhão, Brazil.
Marcelo Souza de AndradePostgraduate Program in Adult Health, Federal University of Maranhão, São Luís, Brazil.
Joyce Santos LagesUniversity Hospital of the Federal University of Maranhão, São Luís, Brazil.
Rita da Graça Carvalhal Frazão CorrêaLaboratory of Immunofluorescence and Electron Microscopy, University Hospital of the Federal University of Maranhão, São Luís, Brazil.
Ana Gabriela Caldas OliveiraDepartment of Medicine, Federal University of Maranhão, São Luís, Maranhão, Brazil.
Eliel Barbosa TeixeiraOncology Research Center, Federal University of Pará, Belém, Pará, Brazil.
Marcelli Geisse de Oliveira Prata da SilvaOncology Research Center, Federal University of Pará, Belém, Pará, Brazil.
Susanne Suely Santos da FonsecaOncology Research Center, Federal University of Pará, Belém, Pará, Brazil.
Antonio Augusto Lima Teixeira-JúniorLaboratory of Immunofluorescence and Electron Microscopy, University Hospital of the Federal University of Maranhão, São Luís, Brazil.
Matheus Silva AlvesState University of the Tocantina Region of Maranhão, Department of Health Sciences, Imperatriz, Maranhão, Brazil.
Antonio Machado Alencar JuniorMolecular Pathology Study Group, University Hospital of the Federal University of Maranhão, São Luís, Brazil.
André Salim KhayatOncology Research Center, Federal University of Pará, Belém, Pará, Brazil.
Jaqueline Diniz PinhoLaboratory of Immunofluorescence and Electron Microscopy, University Hospital of the Federal University of Maranhão, São Luís, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cervical Cancer (CC) is one of the most prevalent neoplasms among women, considered the leading cause of gynecological death worldwide, and the fourth most common type of cancer. Regional metastasis is closely related to the low effectiveness of treatment, and validating biomarkers can optimize accuracy in diagnosis and prognosis. Among the potential biomarkers associated with disease metastasis are circular RNAs (circRNAs), whose altered expression has been linked to CC progression. In this context, this systematic review aims to compile information on the clinical-pathological significance and describe the biological function of circRNAs. Inclusion and exclusion criteria were used to include relevant literature, followed by

Indexed as

biomarkerscervical cancercircRNAsnon-coding RNAsprognosis

Identifiers

PMID38859935
PMCPMC11163134

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.