ArticleFrontiers in aging neuroscience2024
Implications of helplessness in depression: diagnosing mild cognitive impairment and analyzing its effects on cognitive decline in older adults.
Article in Frontiers in aging neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Psychometric properties and age- and gender-specific normative values of the Patient Health Questionnaire-4 among older adults aged 60 years and above.BMC geriatrics · 2026Article
- Caregiving burden, physical activity, psychosocial factors, and maternal cognitive function in mothers of children with developmental disabilities: a cross-sectional study.BMC psychology · 2026Article
- Self-reported hopefulness and cognitive function: the moderating effect of physical activity in older adults without cognitive impairment.Frontiers in aging neuroscience · 2025Article
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9 authors.
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Abstract
Background: This study focuses on how elements of depression correlate with mild cognitive impairment (MCI) in older adults and the diagnostic efficacy of combining these components with the Mini-Mental State Examination (MMSE). The study also investigated the connection between individual depression components and overall cognitive function, as measured by the total score (TS) of the consortium to establish a registry for Alzheimer's disease (AD) assessment battery. Methods: The study included 196 nondemented adults aged 65 to 90 years at a university hospital and community. Comprehensive clinical assessments including the 30-item Geriatric Depression Scale (GDS) to measure components of depressive symptoms, TS, and blood nutritional biomarkers. Results: Our stepwise logistic regression analysis highlighted the 'helplessness item' (odds ratio = 4.531, 95% CI = 2.218 to 9.258, Conclusion: Our findings suggest that helplessness is highly effective in diagnosing MCI and is linked to a decrease in cognitive function. Therefore, when addressing MCI and AD-related cognitive decline, clinicians should consider helplessness.
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