Evidence map›Paper›PMID 38859862›Full record

ArticleAmerican journal of cancer research2024

Effects of methylation and transcription factor YY1 on ID2 expression in non-small cell lung carcinoma cells.

Yi-Hsin Tseng, Wen-Ru Chou, Wei-Lun Liu, Zhong-Xuan Dung, Ching-Hao Lin, Chia-Hung Hsieh, Chi-Chung Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of cancer research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yi-Hsin TsengGraduate Institute of Biomedical and Pharmaceutical Science, Fu Jen Catholic University New Taipei, Taiwan.
Wen-Ru ChouDepartment of Internal Medicine, Fu Jen Catholic University Hospital, Fu Jen Catholic University New Taipei, Taiwan.
Wei-Lun LiuSchool of Medicine, College of Medicine, Fu Jen Catholic University New Taipei, Taiwan.
Zhong-Xuan DungGraduate Institute of Biomedical and Pharmaceutical Science, Fu Jen Catholic University New Taipei, Taiwan.
Ching-Hao LinDepartment of Nephrology, Sijhih Cathay General Hospital New Taipei, Taiwan.
Chia-Hung HsiehGraduate Institute of Biomedical Sciences, China Medical University Taichung, Taiwan.
Chi-Chung WangGraduate Institute of Biomedical and Pharmaceutical Science, Fu Jen Catholic University New Taipei, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The inhibitor of DNA-binding 2 (ID2) plays a major role in tumor dedifferentiation in non-small cell lung cancer (NSCLC). Studies have indicated an inverse correlation between ID2 expression and NSCLC cell invasiveness. However, the mechanisms through which ID2 activation is regulated are currently unclear. We overexpressed ID2 in H1299 cells and extensively characterized their cellular behaviors. By employing a serial deletion approach combined with a reporter assay, we pinpointed the basal promoter region of

Indexed as

inhibitor of DNA-binding protein 2lung adenocarcinomametastasismethylationYY1

Identifiers

PMID38859862
PMCPMC11162666

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.