Evidence map›Paper›PMID 38859854›Full record

ArticleAmerican journal of cancer research2024

Efficacy and advantage of immunotherapy for melanoma

Yueyao Yang, Qian Huang, Mo Cheng, Lu Deng, Xun Liu, Xiufeng Zheng, Jing Wei, Yanna Lei, Xiaoyin Li, Fukun Guo and 5 more

Abstract read
In one paragraph

Article in American journal of cancer research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yueyao YangNational Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University Chengdu 610064, Sichuan, China.
Qian HuangDepartment of Medical Oncology/Gastric Cancer Center, West China Hospital, Sichuan University Chengdu 610041, Sichuan, China.
Mo ChengDepartment of Medical Oncology/Gastric Cancer Center, West China Hospital, Sichuan University Chengdu 610041, Sichuan, China.
Lu DengNational Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University Chengdu 610064, Sichuan, China.
Xun LiuNational Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University Chengdu 610064, Sichuan, China.
Xiufeng ZhengDepartment of Medical Oncology/Gastric Cancer Center, West China Hospital, Sichuan University Chengdu 610041, Sichuan, China.
Jing WeiDepartment of Medical Oncology/Gastric Cancer Center, West China Hospital, Sichuan University Chengdu 610041, Sichuan, China.
Yanna LeiDepartment of Medical Oncology/Gastric Cancer Center, West China Hospital, Sichuan University Chengdu 610041, Sichuan, China.
Xiaoyin LiDepartment of Medical Oncology/Gastric Cancer Center, West China Hospital, Sichuan University Chengdu 610041, Sichuan, China.
Fukun GuoDivision of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center 3333 Burnet Avenue, Cincinnati, OH 45229, USA.
Yu DengSchool of Basic Medical Sciences, Chengdu University Chengdu 610106, Sichuan, China.
Yi ZhengDivision of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center 3333 Burnet Avenue, Cincinnati, OH 45229, USA.
Feng BiDepartment of Medical Oncology, West China Hospital, Sichuan University Chengdu 610041, Sichuan, China.
Gang WangNational Engineering Research Center for Biomaterials, College of Biomedical Engineering, Sichuan University Chengdu 610064, Sichuan, China.
Ming LiuDepartment of Medical Oncology/Gastric Cancer Center, West China Hospital, Sichuan University Chengdu 610041, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunotherapy, in the shape of immune checkpoint inhibitors (ICIs), has completely changed the treatment of cancer. However, the increasing expense of treatment and the frequency of immune-related side effects, which are frequently associated with combination antibody therapies and Fc fragment of antibody, have limited the patient's ability to benefit from these treatments. Herein, we presented the therapeutic effects of the plasmid-encoded PD-1 and CTLA-4 scFvs (single-chain variable fragment) for melanoma

Indexed as

immune-checkpoint inhibitorsImmunotherapyintramuscular expressionmelanomaplasmid

Identifiers

PMID38859854
PMCPMC11162689

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.