Evidence map›Paper›PMID 38858704›Full record

ArticleBMC complementary medicine and therapies2024

Plumieride as a novel anti-fungal and anti-inflammatory iridoid against superficial candidiasis in mice.

Riham A El-Shiekh, Meselhy Rageb Meselhy, Rana Elshimy, Marwa A Ibrahim, Merhan E Ali, Eman I Hassanen

Abstract read
In one paragraph

Article in BMC complementary medicine and therapies, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. New insights on the role of some biometals in mancozeb induced hematological and hepatorenal toxicity in rats and the protective effect of naringin.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Riham A El-ShiekhDepartment of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt. riham.adel@pharma.cu.edu.eg.
Meselhy Rageb MeselhyDepartment of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt.
Rana ElshimyDepartment of Microbiology and Immunology, Faculty of Pharmacy, Ahram Canadian University, Giza, 12573, Egypt.
Marwa A IbrahimDepartment of Biochemistry and Molecular Biology, Faculty of Veterinary Medicine, Cairo University, Giza, 12211, Egypt.
Merhan E AliDepartment of Pathology, Faculty of Veterinary Medicine, Cairo University, Giza, 12211, Egypt.
Eman I HassanenDepartment of Pathology, Faculty of Veterinary Medicine, Cairo University, Giza, 12211, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the past few decades, there has been a notable rise in the occurrence of several types of candidiasis. Candida albicans is the most common cause of superficial fungal infections in humans. In this study, plumieride, one of the major iridoids from Plumeria obtusa L. leaves, was isolated and investigated for its potential against Candida albicans (CA)-induced dermatitis in mice. qRT-PCR was done to assess the impact of plumieride on the expression of the major virulence genes of CA. Five groups (n = 7) of adult male BALB/c mice were categorized into: group I: non-infected mice; group II: mice infected intradermally with 10

Indexed as

Antifungal AgentsAnti-Inflammatory AgentsCandida albicansIridoidsMice, Inbred BALB CAnimalsCandidiasisDisease Models, AnimalMaleMiceAntifungal AgentsAnti-Inflammatory AgentsIridoidsCandida albicansGene expressionInflammationPathologyPlumieride

Identifiers

PMID38858704
PMCPMC11163697

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.