Evidence map›Paper›PMID 38858697›Full record

ArticleBMC medicine2024

Validation of the Health Assessment Tool (HAT) based on four aging cohorts from the Swedish National study on Aging and Care.

Ahmad Abbadi, Emmanouil Kokoroskos, Matthew Stamets, Davide L Vetrano, Nicola Orsini, Sölve Elmståhl, Cecilia Fagerström, Anders Wimo, Anders Sköldunger, Johan Sanmartin Berglund and 4 more

Abstract readValidation Study
In one paragraph

Article in BMC medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ahmad Abbadi *Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Solna, Sweden. ahmad.abbadi@ki.se.ORCID 0000-0001-9373-668X
Emmanouil Kokoroskos *Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Solna, Sweden.ORCID 0009-0007-4250-2294
Matthew StametsAging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Solna, Sweden.ORCID 0009-0000-8702-9233
Davide L VetranoAging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Solna, Sweden.ORCID 0000-0002-3099-4830
Nicola OrsiniDepartment of Global Public Health, Karolinska Institutet, Solna, Sweden.ORCID 0000-0002-2210-5634
Sölve ElmståhlDivision of Geriatric Medicine, Department of Clinical Sciences in Malmö, Lund University, Malmö, Sweden.ORCID 0000-0001-7153-5414
Cecilia FagerströmFaculty of Health and Life Sciences, Linnaeus University, Kalmar, Sweden.ORCID 0000-0002-4257-282X
Anders WimoDivision of Neurogeriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Huddinge, Sweden.ORCID 0000-0003-0963-5750
Anders SköldungerDivision of Neurogeriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Huddinge, Sweden.ORCID 0000-0001-8439-2248
Johan Sanmartin BerglundDepartment of Health, Blekinge Institute of Technology, Karlskrona, Sweden.ORCID 0000-0003-4312-2246
Christina B OlssonDivision of Physiotherapy, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Huddinge, Sweden.ORCID 0000-0003-1300-7765
Caroline WachtlerDivision of Family Medicine and Primary Care, Department of Neurobiology, Care Sciences, and Society, Karolinska Institutet, Huddinge, Sweden.ORCID 0000-0002-1317-7732
Laura FratiglioniAging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Solna, Sweden.ORCID 0000-0002-6374-6614
Amaia Calderón-LarrañagaAging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Solna, Sweden.ORCID 0000-0001-9064-9222

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAs global aging accelerates, routinely assessing the functional status and morbidity burden of older patients becomes paramount. The aim of this study is to assess the validity of the comprehensive clinical and functional Health Assessment Tool (HAT) based on four cohorts of older adults (60 + years) from the Swedish National study on Aging and Care (SNAC) spanning urban, suburban, and rural areas.

methodsThe HAT integrates five health indicators (gait speed, global cognition, number of chronic diseases, and basic and instrumental activities of daily living), providing an individual-level score between 0 and 10. The tool was constructed using nominal response models, first separately for each cohort and then in a harmonized dataset. Outcomes included all-cause mortality over a maximum follow-up of 16 years and unplanned hospital admissions over a maximum of 3 years of follow-up. The predictive capacity was assessed through the area under the curve (AUC) using logistic regressions. For time to death, Cox regressions were performed, and Harrell's C-indices were reported. Results from the four cohorts were pooled using individual participant data meta-analysis and compared with those from the harmonized dataset.

resultsThe HAT demonstrated high predictive capacity across all cohorts as well as in the harmonized dataset. In the harmonized dataset, the AUC was 0.84 (95% CI 0.81-0.87) for 1-year mortality, 0.81 (95% CI 0.80-0.83) for 3-year mortality, 0.80 (95% CI 0.79-0.82) for 5-year mortality, 0.69 (95% CI 0.67-0.70) for 1-year unplanned admissions, and 0.69 (95% CI 0.68-0.70) for 3-year unplanned admissions. The Harrell's C for time-to-death throughout 16 years of follow-up was 0.75 (95% CI 0.74-0.75).

conclusionsThe HAT is a highly predictive, clinically intuitive, and externally valid instrument with potential for better addressing older adults' health needs and optimizing risk stratification at the population level.

Indexed as

Geriatric AssessmentActivities of Daily LivingAgedAged, 80 and overAgingChronic DiseaseCohort StudiesFemaleHumansMaleMiddle AgedSwedenAging cohortsExternal validationFrailtyGeriatric health assessment

Identifiers

PMID38858697
PMCPMC11165739

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