Evidence map›Paper›PMID 38858392›Full record

ArticleNutrition & diabetes2024

Vitamin D is involved in the effects of the intestinal flora and its related metabolite TMAO on perirenal fat and kidneys in mice with DKD.

Xiaodi Zheng, Yuhong Huang, Mengxue Yang, Lulu Jin, Xuemeng Zhang, Rui Zhang, Yueyue Wu, Cuili Yan, Yuan Gao, Miao Zeng and 5 more

Abstract read
In one paragraph

Article in Nutrition & diabetes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. Microbiota-gut-kidney axis in health and renal disease.International journal of biological sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Xiaodi Zheng *Department of Endocrinology, Shanghai Fifth People's Hospital, Fudan University, Shanghai, 200240, China.
Yuhong Huang *Department of Endocrinology, Shanghai Fifth People's Hospital, Fudan University, Shanghai, 200240, China.
Mengxue YangDepartment of Endocrinology, Shanghai Fifth People's Hospital, Fudan University, Shanghai, 200240, China. yangmengxue01@126.com.
Lulu JinDepartment of Endocrinology, Shanghai Fifth People's Hospital, Fudan University, Shanghai, 200240, China.
Xuemeng ZhangCommunity Health Research Center, Fudan University, Shanghai, 200240, China.
Rui ZhangDepartment of Endocrinology, Shanghai Fifth People's Hospital, Fudan University, Shanghai, 200240, China.
Yueyue WuDepartment of Endocrinology, Shanghai Fifth People's Hospital, Fudan University, Shanghai, 200240, China.
Cuili YanDepartment of Endocrinology, Shanghai Fifth People's Hospital, Fudan University, Shanghai, 200240, China.
Yuan GaoPujiang Community Health Service Center, Minhang District, Shanghai, 2011112, China.
Miao ZengDepartment of Infectious Diseases, Shanghai Fifth People's Hospital, Fudan University, Shanghai, 200240, China.
Fei LiDepartment of Endocrinology, Affiliated Hospital of Zunyi Medical University, Guizhou, 563000, China.
Xue ZhouDepartment of Endocrinology, Affiliated Hospital of Zunyi Medical University, Guizhou, 563000, China.
Neng ZhangDepartment of Endocrinology, Affiliated Hospital of Zunyi Medical University, Guizhou, 563000, China.
Jun LiuDepartment of Endocrinology, Shanghai Fifth People's Hospital, Fudan University, Shanghai, 200240, China.
Bingbing ZhaDepartment of Endocrinology, Shanghai Fifth People's Hospital, Fudan University, Shanghai, 200240, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVitamin D was shown to directly exert a protective effect on diabetic kidney disease (DKD) in our previous study. However, whether it has an effect on perirenal adipose tissue (PRAT) or the intestinal flora and its metabolites (trimethylamine N-oxide, TMAO) is unclear.

methodsDKD mice were received different concentrations of 1,25-(OH)

results1,25-(OH)

conclusionsThe protective effect of 1,25-(OH)

Indexed as

Diabetic NephropathiesGastrointestinal MicrobiomeKidneyMethylaminesMice, KnockoutReceptors, CalcitriolAdipose TissueAnimalsCalcitriolMaleMiceMice, Inbred C57BLVitamin DCalcitriolMethylaminesReceptors, CalcitrioltrimethyloxamineVitamin D

Identifiers

PMID38858392
PMCPMC11164932

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.