Evidence map›Paper›PMID 38858365›Full record

ArticleNature communications2024

Identification and characterization of Varicella Zoster Virus circular RNA in lytic infection.

Shaomin Yang, Di Cao, Dabbu Kumar Jaijyan, Mei Wang, Jian Liu, Ruth Cruz-Cosme, Songbin Wu, Jiabin Huang, Mulan Zeng, Xiaolian Liu and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Varicella zoster virus and the central nervous system.Nature reviews. Microbiology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Shaomin Yang *Department of Pain Medicine and Shenzhen Municipal Key Laboratory for Pain Medicine, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China.
Di Cao *Department of Pain Medicine and Shenzhen Municipal Key Laboratory for Pain Medicine, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China.
Dabbu Kumar Jaijyan *Department of Microbiology and Molecular Genetics, New Jersey Medical School, Rutgers University, 225 Warren Street, Newark, NJ, 070101, USA.
Mei WangInstitute of Medical Microbiology, Jinan University, Guangzhou, Guangdong, 510632, China.
Jian LiuSchool of Biological Sciences and Biotechnology, Minnan Normal University, Zhangzhou, 363000, China.
Ruth Cruz-CosmeDepartment of Microbiology, Howard University College of Medicine, 520 W Street NW, Washington, DC, 20059, USA.
Songbin WuDepartment of Pain Medicine and Shenzhen Municipal Key Laboratory for Pain Medicine, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China.
Jiabin HuangDepartment of Pain Medicine and Shenzhen Municipal Key Laboratory for Pain Medicine, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China.
Mulan ZengDepartment of Microbiology and Molecular Genetics, New Jersey Medical School, Rutgers University, 225 Warren Street, Newark, NJ, 070101, USA.ORCID http://orcid.org/0009-0004-8494-9236
Xiaolian LiuInstitute of Medical Microbiology, Jinan University, Guangzhou, Guangdong, 510632, China.
Wuping SunDepartment of Pain Medicine and Shenzhen Municipal Key Laboratory for Pain Medicine, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China.
Donglin XiongDepartment of Pain Medicine and Shenzhen Municipal Key Laboratory for Pain Medicine, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China.
Qiyi TangDepartment of Microbiology, Howard University College of Medicine, 520 W Street NW, Washington, DC, 20059, USA. qiyi.tang@howard.edu.ORCID http://orcid.org/0000-0002-6487-2356
Lizu XiaoDepartment of Pain Medicine and Shenzhen Municipal Key Laboratory for Pain Medicine, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China. nsyyjoe@live.cn.
Hua ZhuDepartment of Microbiology and Molecular Genetics, New Jersey Medical School, Rutgers University, 225 Warren Street, Newark, NJ, 070101, USA. hua.zhu@rutgers.edu.

Funding

Sleep Disorders in Adults with Sickle Cell Disease: Frequency, Associations with Cardiovascular and Pain Indicators, and Responses to TreatmentU54MD007597 · NIMHD · HOWARD UNIVERSITY · PI William M. Southerland · 2019 to 2026
$37.7M
PROTEOMICS CORE FACILITYG12MD007597 · NIMHD · HOWARD UNIVERSITY · PI SOUTHERLAND, WILLIAM M. · 2012 to 2018
$14.8M
NIMHD NIH HHS G12 MD007597NIMHD NIH HHS U54 MD007597
6 · The paper itself

Abstract

This study investigates the role of circular RNAs (circRNAs) in the context of Varicella-Zoster Virus (VZV) lytic infection. We employ two sequencing technologies, short-read sequencing and long-read sequencing, following RNase R treatment on VZV-infected neuroblastoma cells to identify and characterize both cellular and viral circRNAs. Our large scanning analysis identifies and subsequent experiments confirm 200 VZV circRNAs. Moreover, we discover numerous VZV latency-associated transcripts (VLTs)-like circRNAs (circVLTs

Indexed as

Herpesvirus 3, HumanRNA, CircularRNA, ViralVirus ReplicationAcyclovirCell Line, TumorExonsHumansVaricella Zoster Virus InfectionVirus LatencyAcyclovirRNA, CircularRNA, Viral

Identifiers

PMID38858365
PMCPMC11164961

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.