Evidence map›Paper›PMID 38858223›Full record

ArticleJournal of prosthodontics : official journal of the American College of Prosthodontists2025

In vitro analysis of monomer leaching in modern dental materials: CAD milled, printed, traditional heat-processed, and auto-polymerizing denture base resins.

Greta Smidt, Shang Gao, Divya Iyer, Samanvaya Srivastava, Kumar C Shah

Abstract read
In one paragraph

Article in Journal of prosthodontics : official journal of the American College of Prosthodontists, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Greta SmidtAdvanced Graduate Prosthodontics Department, University of California School of Dentistry, Los Angeles, California, USA.ORCID https://orcid.org/0009-0006-6296-1730
Shang GaoChemical and Biomolecular Engineering Department, University of California, Los Angeles, California, USA.
Divya IyerChemical and Biomolecular Engineering Department, University of California, Los Angeles, California, USA.
Samanvaya SrivastavaChemical and Biomolecular Engineering Department, University of California, Los Angeles, California, USA.
Kumar C ShahFaculty Group Dental Practice, University of California School of Dentistry, Los Angeles, California, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDenture fabrication has shifted from traditional heat-processed and auto-polymerizing materials to computer-aided design and computer-aided manufacturing (CAD-CAM) milled and printed materials. The monomer in traditional materials can induce an allergic reaction in some patients. With the rise in the edentulous population and increasing demand for the fabrication of dentures, these newer materials should be studied for monomer leaching. The purpose of this study was to evaluate the ratio of residual monomer in materials being used for denture bases: CAD-milled polymethylmethacrylate (PMMA), printed denture base resin, heat-processed PMMA, and auto-polymerizing PMMA comparatively. MATERIALS AND

methodsMilled, printed, heat-activated, and auto-polymerizing denture base specimens (n = 3 for each group, each test run three times) were fabricated according to manufacturer recommendations. Specimens were first immersed in deuterated chloroform (CDCl

resultsWhile the heat-processed, auto-polymerizing, and milled specimens possessed residual monomers, no significant monomer leaching was noted in the printed specimen, while immersed in CDCl

conclusionsResidual monomers were not found in the printed denture material in this study in either CDCl

Indexed as

Acrylic ResinsComputer-Aided DesignDental MaterialsDenture BasesPolymethyl MethacrylateDenture DesignHot TemperatureIn Vitro TechniquesMaterials TestingPolymerizationAcrylic ResinsDental MaterialsPolymethyl Methacrylatedenture basedenturesmonomerpolymer

Identifiers

PMID38858223
PMCPMC12679680

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.