Evidence map›Paper›PMID 38858139›Full record

Trial reportBMJ open2024

Maternal and child health intervention to promote behaviour change: a population-level cluster-randomised controlled trial in Honduras.

William Oles, Marcus Alexander, Rennie Negron, Jennifer Nelson, Emma Iriarte, Edoardo M Airoldi, Nicholas A Christakis, Laura Forastiere

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02694679 (Randomized Controlled Trial of Social Network Targeting to Magnify Population-Level MNCH Behavior Change in Honduras), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02694679 nacompletednot on this map

Randomized Controlled Trial of Social Network Targeting to Magnify Population-Level MNCH Behavior Change in Honduras

TypeinterventionalSponsorYale UniversityRan2015 to 2020Enrolled31,195ConditionsPreterm Delivery, Hypothermia, Diarrhea, Upper Respiratory InfectionArmsCBNH
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

William Oles *Yale Institute for Network Science, Yale University, New Haven, Connecticut, USA.ORCID 0000-0003-1125-6717
Marcus Alexander *Yale Institute for Network Science, Yale University, New Haven, Connecticut, USA.ORCID 0000-0001-8627-7534
Rennie NegronInstitute for Health Equity Research, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Jennifer NelsonInter-American Development Bank, Washington, District of Columbia, USA.
Emma IriarteInter-American Development Bank, Washington, District of Columbia, USA.
Edoardo M AiroldiDepartment of Statistics, Operations, and Data Science, Fox School of Business, Temple University, Philadelphia, Pennsylvania, USA.
Nicholas A ChristakisYale Institute for Network Science, Yale University, New Haven, Connecticut, USA.ORCID 0000-0001-5547-1086
Laura ForastiereYale Institute for Network Science, Yale University, New Haven, Connecticut, USA laura.forastiere@yale.edu.ORCID 0000-0003-3721-9826

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Developing causal inference methods to evaluate and leverage spillover effects through social Interactions for designing improved HIV prevention interventionsR01MH134715 · NIMH · YALE UNIVERSITY · PI Laura Forastiere · 2023 to 2026
$3.1M
NCATS NIH HHS UL1 TR001863NIMH NIH HHS R01 MH134715
6 · The paper itself

Abstract

objectivesTo assess the efficacy of a sustained educational intervention to affect diverse outcomes across the pregnancy and infancy timeline.

settingA multi-arm cluster-randomised controlled trial in 99 villages in Honduras' Copán region, involving 16 301 people in 5633 households from October 2015 to December 2019.

participantsResidents aged 12 and older were eligible. A photographic census involved 93% of the population, with 13 881 and 10 263 individuals completing baseline and endline surveys, respectively.

intervention22-month household-based counselling intervention aiming to improve practices, knowledge and attitudes related to maternal, neonatal and child health. PRIMARY AND SECONDARY OUTCOME MEASURES: Primary outcomes were prenatal/postnatal care behaviours, facility births, exclusive breast feeding, parental involvement, treatment of diarrhoea and respiratory illness, reproductive health, and gender/reproductive norms. Secondary outcomes were knowledge and attitudes related to the primary outcomes.

resultsParents targeted for the intervention were 16.4% (95% CI 3.1%-29.8%, p=0.016) more likely to have their newborn's health checked in a health facility within 3 days of birth; 19.6% (95% CI 4.2%-35.1%, p=0.013) more likely to not wrap a fajero around the umbilical cord in the first week after birth; and 8.9% (95% CI 0.3%-17.5%, p=0.043) more likely to report that the mother breast fed immediately after birth. Changes in knowledge and attitudes related to these primary outcomes were also observed. We found no significant effect on various other practices.

conclusionA sustained counselling intervention delivered in the home setting by community health workers can meaningfully change practices, knowledge and attitudes related to proper newborn care following birth, including professional care-seeking, umbilical cord care and breast feeding. TRIAL REGISTRATION NUMBER: NCT02694679.

Indexed as

Health Knowledge, Attitudes, PracticeAdolescentAdultBreast FeedingChildChild HealthCounselingFemaleHealth PromotionHondurasHumansInfantInfant, NewbornMalePostnatal CarePregnancycommunity child healthmaternal medicinepublic healthstatistics & research methods

Identifiers

PMID38858139
PMCPMC11168147

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.